Physiological IRE-1-XBP-1 and PEK-1 Signaling in Caenorhabditis elegans Larval Development and Immunity

Physiological IRE-1-XBP-1 and PEK-1 Signaling in Caenorhabditis elegans Larval Development and Immunity

Endoplasmic reticulum (ER) stress activates the Unfolded Protein Response, a compensatory signaling response that is mediated by the IRE-1, PERK/PEK-1, and ATF-6 pathways in metazoans. Genetic studies have implicated roles for UPR signaling in animal development and disease, but the function of the...

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Bibliographic Details
Main Authors:	Kim, Dennis H., Richardson, Claire Elissa, Kinkel, Stephanie
Other Authors:	Massachusetts Institute of Technology. Department of Biology
Format:	Article
Language:	en_US
Published:	Public Library of Science 2012
Online Access:	http://hdl.handle.net/1721.1/69167 https://orcid.org/0000-0002-4109-5152

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