Waking up dormant tumors
As appreciation grows for the contribution of the tumor microenvironment to the progression of cancer, new evidence accumulates to support that the participation of stromal cells can extend beyond the local environment. Recently, Elkabets and colleagues demonstrated a systemic interaction between ca...
| Main Authors: | , |
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| Other Authors: | |
| Format: | Article |
| Language: | en_US |
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BioMed Central Ltd.
2012
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| Online Access: | http://hdl.handle.net/1721.1/69535 |
| _version_ | 1811079770717290496 |
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| author | Tse, Joyce C. Kalluri, Raghu |
| author2 | Harvard University--MIT Division of Health Sciences and Technology |
| author_facet | Harvard University--MIT Division of Health Sciences and Technology Tse, Joyce C. Kalluri, Raghu |
| author_sort | Tse, Joyce C. |
| collection | MIT |
| description | As appreciation grows for the contribution of the tumor microenvironment to the progression of cancer, new evidence accumulates to support that the participation of stromal cells can extend beyond the local environment. Recently, Elkabets and colleagues demonstrated a systemic interaction between cancer cells and distant bone marrow cells to support the growth of otherwise indolent tumor cells at a secondary site, raising thought-provoking questions regarding the involvement of stromal cells in maintaining metastatic dormancy. |
| first_indexed | 2024-09-23T11:20:12Z |
| format | Article |
| id | mit-1721.1/69535 |
| institution | Massachusetts Institute of Technology |
| language | en_US |
| last_indexed | 2024-09-23T11:20:12Z |
| publishDate | 2012 |
| publisher | BioMed Central Ltd. |
| record_format | dspace |
| spelling | mit-1721.1/695352022-09-27T18:48:23Z Waking up dormant tumors Tse, Joyce C. Kalluri, Raghu Harvard University--MIT Division of Health Sciences and Technology Kalluri, Raghu Kalluri, Raghu As appreciation grows for the contribution of the tumor microenvironment to the progression of cancer, new evidence accumulates to support that the participation of stromal cells can extend beyond the local environment. Recently, Elkabets and colleagues demonstrated a systemic interaction between cancer cells and distant bone marrow cells to support the growth of otherwise indolent tumor cells at a secondary site, raising thought-provoking questions regarding the involvement of stromal cells in maintaining metastatic dormancy. National Institutes of Health (U.S.) (NIH grant CA125550) National Institutes of Health (U.S.) (NIH grant CA155370) National Institutes of Health (U.S.) (NIH grant CA151925) National Institutes of Health (U.S.) (NIH grant DK081576) United States. Dept. of Defense (Breast Cancer Research Program Predoctoral Traineeship Award) 2012-03-01T16:36:53Z 2012-03-01T16:36:53Z 2011-06 Article http://purl.org/eprint/type/JournalArticle 1465-5411 http://hdl.handle.net/1721.1/69535 Tse, Joyce C, and Raghu Kalluri. “Waking up Dormant Tumors.” Breast Cancer Research 13.3 (2011): 310. © 2011 BioMed Central Ltd. en_US http://dx.doi.org/10.1186/bcr2872 Breast Cancer Research Creative Commons Attribution http://creativecommons.org/licenses/by/2.0 application/pdf BioMed Central Ltd. BioMed Central |
| spellingShingle | Tse, Joyce C. Kalluri, Raghu Waking up dormant tumors |
| title | Waking up dormant tumors |
| title_full | Waking up dormant tumors |
| title_fullStr | Waking up dormant tumors |
| title_full_unstemmed | Waking up dormant tumors |
| title_short | Waking up dormant tumors |
| title_sort | waking up dormant tumors |
| url | http://hdl.handle.net/1721.1/69535 |
| work_keys_str_mv | AT tsejoycec wakingupdormanttumors AT kalluriraghu wakingupdormanttumors |