Endo-Selective Enyne Ring- Closing Metathesis Promoted by Stereogenic-at-W Mono-Pyrrolide Complexes
The utility of W-alkylidene complexes for enyne ring-closing metathesis is demonstrated in a direct comparison with Mo-based analogs. Tungsten complexes lead to less alkyne oligomerization and higher levels of endo-selectivity and enantioselectivity.
| Main Authors: | , , |
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| Other Authors: | |
| Format: | Article |
| Language: | en_US |
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American Chemical Society
2012
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| Online Access: | http://hdl.handle.net/1721.1/69936 https://orcid.org/0000-0001-5827-3552 |
| _version_ | 1826202321452793856 |
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| author | Zhao, Yu Hoveyda, Amir H. Schrock, Richard Royce |
| author2 | Massachusetts Institute of Technology. Department of Chemistry |
| author_facet | Massachusetts Institute of Technology. Department of Chemistry Zhao, Yu Hoveyda, Amir H. Schrock, Richard Royce |
| author_sort | Zhao, Yu |
| collection | MIT |
| description | The utility of W-alkylidene complexes for enyne ring-closing metathesis is demonstrated in a direct comparison with Mo-based analogs. Tungsten complexes lead to less alkyne oligomerization and higher levels of endo-selectivity and enantioselectivity. |
| first_indexed | 2024-09-23T12:05:40Z |
| format | Article |
| id | mit-1721.1/69936 |
| institution | Massachusetts Institute of Technology |
| language | en_US |
| last_indexed | 2024-09-23T12:05:40Z |
| publishDate | 2012 |
| publisher | American Chemical Society |
| record_format | dspace |
| spelling | mit-1721.1/699362022-10-01T08:06:29Z Endo-Selective Enyne Ring- Closing Metathesis Promoted by Stereogenic-at-W Mono-Pyrrolide Complexes Zhao, Yu Hoveyda, Amir H. Schrock, Richard Royce Massachusetts Institute of Technology. Department of Chemistry Schrock, Richard Royce Schrock, Richard Royce Zhao, Yu The utility of W-alkylidene complexes for enyne ring-closing metathesis is demonstrated in a direct comparison with Mo-based analogs. Tungsten complexes lead to less alkyne oligomerization and higher levels of endo-selectivity and enantioselectivity. National Institutes of Health (U.S.) (GM-59426) 2012-04-04T20:00:34Z 2012-04-04T20:00:34Z 2011-01 2010-12 Article http://purl.org/eprint/type/JournalArticle 1523-7060 1523-7052 http://hdl.handle.net/1721.1/69936 Zhao, Yu, Amir H. Hoveyda, and Richard R. Schrock. “Endo-Selective Enyne Ring-Closing Metathesis Promoted by Stereogenic-at-W Mono-Pyrrolide Complexes.” Organic Letters 13.4 (2011): 784–787. https://orcid.org/0000-0001-5827-3552 en_US http://dx.doi.org/10.1021/ol1030525 Organic Letters Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use. application/pdf American Chemical Society Prof. Schrock via Erja Kajosalo |
| spellingShingle | Zhao, Yu Hoveyda, Amir H. Schrock, Richard Royce Endo-Selective Enyne Ring- Closing Metathesis Promoted by Stereogenic-at-W Mono-Pyrrolide Complexes |
| title | Endo-Selective Enyne Ring- Closing Metathesis Promoted by Stereogenic-at-W Mono-Pyrrolide Complexes |
| title_full | Endo-Selective Enyne Ring- Closing Metathesis Promoted by Stereogenic-at-W Mono-Pyrrolide Complexes |
| title_fullStr | Endo-Selective Enyne Ring- Closing Metathesis Promoted by Stereogenic-at-W Mono-Pyrrolide Complexes |
| title_full_unstemmed | Endo-Selective Enyne Ring- Closing Metathesis Promoted by Stereogenic-at-W Mono-Pyrrolide Complexes |
| title_short | Endo-Selective Enyne Ring- Closing Metathesis Promoted by Stereogenic-at-W Mono-Pyrrolide Complexes |
| title_sort | endo selective enyne ring closing metathesis promoted by stereogenic at w mono pyrrolide complexes |
| url | http://hdl.handle.net/1721.1/69936 https://orcid.org/0000-0001-5827-3552 |
| work_keys_str_mv | AT zhaoyu endoselectiveenyneringclosingmetathesispromotedbystereogenicatwmonopyrrolidecomplexes AT hoveydaamirh endoselectiveenyneringclosingmetathesispromotedbystereogenicatwmonopyrrolidecomplexes AT schrockrichardroyce endoselectiveenyneringclosingmetathesispromotedbystereogenicatwmonopyrrolidecomplexes |