Shared and selective neural correlates of inhibition, facilitation, and shifting processes during executive control
A network of prefrontal and parietal regions has been implicated in executive control processes. However, the extent to which individual regions within this network are engaged in component control processes, such as inhibition of task-irrelevant stimulus attributes or shifting (switching) between a...
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| Format: | Article |
| Language: | en_US |
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Elsevier
2012
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| Online Access: | http://hdl.handle.net/1721.1/69956 https://orcid.org/0000-0002-6292-2938 https://orcid.org/0000-0003-1158-5692 |
| _version_ | 1826216649309552640 |
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| author | Hedden, Trey Gabrieli, John D. E. |
| author2 | Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences |
| author_facet | Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences Hedden, Trey Gabrieli, John D. E. |
| author_sort | Hedden, Trey |
| collection | MIT |
| description | A network of prefrontal and parietal regions has been implicated in executive control processes. However, the extent to which individual regions within this network are engaged in component control processes, such as inhibition of task-irrelevant stimulus attributes or shifting (switching) between attentional foci, remains controversial. Participants (N = 17) underwent functional magnetic resonance imaging while performing a global–local task in which the global and local levels could facilitate or interfere with one another. Stimuli were presented in blocks in which participants either constantly shifted between the global and local levels, or consistently responded to one level only. Activations related to inhibition and shifting processes were observed in a large network of bilateral prefrontal, parietal, and basal ganglia regions. Region of interest analyses were used to classify each region within this network as being common to inhibition and shifting, or preferential to one component process. Several regions were classified as being preferential to inhibition, including regions within the dorsolateral and ventrolateral prefrontal cortex, the parietal lobes, and the temporal–parietal junction. A limited set of regions in the parietal lobes and left dorsolateral prefrontal cortex were classified as preferential to shifting. There was a very large set of regions displaying activation common to both inhibition and shifting processes, including regions within the dorsolateral prefrontal cortex, anterior cingulate, and basal ganglia. Several of these common regions were also involved during facilitation, suggesting that they are responsive to the number of task-salient channels of information, rather than purely to demands on control processes. |
| first_indexed | 2024-09-23T16:50:47Z |
| format | Article |
| id | mit-1721.1/69956 |
| institution | Massachusetts Institute of Technology |
| language | en_US |
| last_indexed | 2024-09-23T16:50:47Z |
| publishDate | 2012 |
| publisher | Elsevier |
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| spelling | mit-1721.1/699562022-09-29T21:54:25Z Shared and selective neural correlates of inhibition, facilitation, and shifting processes during executive control Hedden, Trey Gabrieli, John D. E. Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences McGovern Institute for Brain Research at MIT Gabrieli, John D. E. Hedden, Trey Gabrieli, John D. E. A network of prefrontal and parietal regions has been implicated in executive control processes. However, the extent to which individual regions within this network are engaged in component control processes, such as inhibition of task-irrelevant stimulus attributes or shifting (switching) between attentional foci, remains controversial. Participants (N = 17) underwent functional magnetic resonance imaging while performing a global–local task in which the global and local levels could facilitate or interfere with one another. Stimuli were presented in blocks in which participants either constantly shifted between the global and local levels, or consistently responded to one level only. Activations related to inhibition and shifting processes were observed in a large network of bilateral prefrontal, parietal, and basal ganglia regions. Region of interest analyses were used to classify each region within this network as being common to inhibition and shifting, or preferential to one component process. Several regions were classified as being preferential to inhibition, including regions within the dorsolateral and ventrolateral prefrontal cortex, the parietal lobes, and the temporal–parietal junction. A limited set of regions in the parietal lobes and left dorsolateral prefrontal cortex were classified as preferential to shifting. There was a very large set of regions displaying activation common to both inhibition and shifting processes, including regions within the dorsolateral prefrontal cortex, anterior cingulate, and basal ganglia. Several of these common regions were also involved during facilitation, suggesting that they are responsive to the number of task-salient channels of information, rather than purely to demands on control processes. National Institute of Mental Health (U.S.) (MH061426) National Institute on Aging (AG021847) 2012-04-05T17:24:04Z 2012-04-05T17:24:04Z 2010-02 2010-01 Article http://purl.org/eprint/type/JournalArticle 1053-8119 1095-9572 http://hdl.handle.net/1721.1/69956 Hedden, Trey, and John D.E. Gabrieli. “Shared and Selective Neural Correlates of Inhibition, Facilitation, and Shifting Processes During Executive Control.” NeuroImage 51.1 (2010): 421–431. Web. 5 Apr. 2012. https://orcid.org/0000-0002-6292-2938 https://orcid.org/0000-0003-1158-5692 en_US http://dx.doi.org/10.1016/j.neuroimage.2010.01.089 NeuroImage Creative Commons Attribution-Noncommercial-Share Alike 3.0 http://creativecommons.org/licenses/by-nc-sa/3.0/ application/pdf Elsevier PubMed Central |
| spellingShingle | Hedden, Trey Gabrieli, John D. E. Shared and selective neural correlates of inhibition, facilitation, and shifting processes during executive control |
| title | Shared and selective neural correlates of inhibition, facilitation, and shifting processes during executive control |
| title_full | Shared and selective neural correlates of inhibition, facilitation, and shifting processes during executive control |
| title_fullStr | Shared and selective neural correlates of inhibition, facilitation, and shifting processes during executive control |
| title_full_unstemmed | Shared and selective neural correlates of inhibition, facilitation, and shifting processes during executive control |
| title_short | Shared and selective neural correlates of inhibition, facilitation, and shifting processes during executive control |
| title_sort | shared and selective neural correlates of inhibition facilitation and shifting processes during executive control |
| url | http://hdl.handle.net/1721.1/69956 https://orcid.org/0000-0002-6292-2938 https://orcid.org/0000-0003-1158-5692 |
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