A multifaceted analysis of HIV-1 protease multidrug resistance phenotypes

A multifaceted analysis of HIV-1 protease multidrug resistance phenotypes

Background Great strides have been made in the effective treatment of HIV-1 with the development of second-generation protease inhibitors (PIs) that are effective against historically multi-PI-resistant HIV-1 variants. Nevertheless, mutation patterns that confer decreasing susceptibility to availabl...

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Bibliographic Details
Main Authors: Doherty, Kathleen M, Nakka, Priyanka, King, Bracken Matheny, Rhee, Soo-Yon, Holmes, Susan P, Shafer, Robert W, Radhakrishnan, Mala L
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:English
Published: BioMed Central Ltd. 2012
Online Access:http://hdl.handle.net/1721.1/70131

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