2D-3D Rigid-Body Registration of X-Ray Fluoroscopy and CT Images

The registration of pre-operative volumetric datasets to intra- operative two-dimensional images provides an improved way of verifying patient position and medical instrument loca- tion. In applications from orthopedics to neurosurgery, it has a great value in maintaining up-to-date information abou...

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Main Author: Zollei, Lilla
Language:en_US
Published: 2004
Subjects:
Online Access:http://hdl.handle.net/1721.1/7078
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author Zollei, Lilla
author_facet Zollei, Lilla
author_sort Zollei, Lilla
collection MIT
description The registration of pre-operative volumetric datasets to intra- operative two-dimensional images provides an improved way of verifying patient position and medical instrument loca- tion. In applications from orthopedics to neurosurgery, it has a great value in maintaining up-to-date information about changes due to intervention. We propose a mutual information- based registration algorithm to establish the proper align- ment. For optimization purposes, we compare the perfor- mance of the non-gradient Powell method and two slightly di erent versions of a stochastic gradient ascent strategy: one using a sparsely sampled histogramming approach and the other Parzen windowing to carry out probability density approximation. Our main contribution lies in adopting the stochastic ap- proximation scheme successfully applied in 3D-3D registra- tion problems to the 2D-3D scenario, which obviates the need for the generation of full DRRs at each iteration of pose op- timization. This facilitates a considerable savings in compu- tation expense. We also introduce a new probability density estimator for image intensities via sparse histogramming, de- rive gradient estimates for the density measures required by the maximization procedure and introduce the framework for a multiresolution strategy to the problem. Registration results are presented on uoroscopy and CT datasets of a plastic pelvis and a real skull, and on a high-resolution CT- derived simulated dataset of a real skull, a plastic skull, a plastic pelvis and a plastic lumbar spine segment.
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spelling mit-1721.1/70782019-04-10T11:52:32Z 2D-3D Rigid-Body Registration of X-Ray Fluoroscopy and CT Images Zollei, Lilla AI registration medical imaging The registration of pre-operative volumetric datasets to intra- operative two-dimensional images provides an improved way of verifying patient position and medical instrument loca- tion. In applications from orthopedics to neurosurgery, it has a great value in maintaining up-to-date information about changes due to intervention. We propose a mutual information- based registration algorithm to establish the proper align- ment. For optimization purposes, we compare the perfor- mance of the non-gradient Powell method and two slightly di erent versions of a stochastic gradient ascent strategy: one using a sparsely sampled histogramming approach and the other Parzen windowing to carry out probability density approximation. Our main contribution lies in adopting the stochastic ap- proximation scheme successfully applied in 3D-3D registra- tion problems to the 2D-3D scenario, which obviates the need for the generation of full DRRs at each iteration of pose op- timization. This facilitates a considerable savings in compu- tation expense. We also introduce a new probability density estimator for image intensities via sparse histogramming, de- rive gradient estimates for the density measures required by the maximization procedure and introduce the framework for a multiresolution strategy to the problem. Registration results are presented on uoroscopy and CT datasets of a plastic pelvis and a real skull, and on a high-resolution CT- derived simulated dataset of a real skull, a plastic skull, a plastic pelvis and a plastic lumbar spine segment. 2004-10-20T20:28:33Z 2004-10-20T20:28:33Z 2001-08-01 AITR-2002-001 http://hdl.handle.net/1721.1/7078 en_US AITR-2002-001 128 p. 21043480 bytes 1712245 bytes application/postscript application/pdf application/postscript application/pdf
spellingShingle AI
registration
medical imaging
Zollei, Lilla
2D-3D Rigid-Body Registration of X-Ray Fluoroscopy and CT Images
title 2D-3D Rigid-Body Registration of X-Ray Fluoroscopy and CT Images
title_full 2D-3D Rigid-Body Registration of X-Ray Fluoroscopy and CT Images
title_fullStr 2D-3D Rigid-Body Registration of X-Ray Fluoroscopy and CT Images
title_full_unstemmed 2D-3D Rigid-Body Registration of X-Ray Fluoroscopy and CT Images
title_short 2D-3D Rigid-Body Registration of X-Ray Fluoroscopy and CT Images
title_sort 2d 3d rigid body registration of x ray fluoroscopy and ct images
topic AI
registration
medical imaging
url http://hdl.handle.net/1721.1/7078
work_keys_str_mv AT zolleililla 2d3drigidbodyregistrationofxrayfluoroscopyandctimages