Predicting transcription factor specificity with all-atom models

Predicting transcription factor specificity with all-atom models

The binding of a transcription factor (TF) to a DNA operator site can initiate or repress the expression of a gene. Computational prediction of sites recognized by a TF has traditionally relied upon knowledge of several cognate sites, rather than an ab initio approach. Here, we examine the possibili...

书目详细资料
Main Authors:	Virnau, Peter, Rahi, Sahand Jamal, Mirny, Leonid A., Kardar, Mehran
其他作者:	Harvard University--MIT Division of Health Sciences and Technology
格式:	文件
语言:	en_US
出版:	Oxford University Press (OUP) 2012
在线阅读:	http://hdl.handle.net/1721.1/70954 https://orcid.org/0000-0002-0785-5410 https://orcid.org/0000-0002-1112-5912

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