Predicting transcription factor specificity with all-atom models
The binding of a transcription factor (TF) to a DNA operator site can initiate or repress the expression of a gene. Computational prediction of sites recognized by a TF has traditionally relied upon knowledge of several cognate sites, rather than an ab initio approach. Here, we examine the possibili...
Main Authors: | Virnau, Peter, Rahi, Sahand Jamal, Mirny, Leonid A., Kardar, Mehran |
---|---|
Other Authors: | Harvard University--MIT Division of Health Sciences and Technology |
Format: | Article |
Language: | en_US |
Published: |
Oxford University Press (OUP)
2012
|
Online Access: | http://hdl.handle.net/1721.1/70954 https://orcid.org/0000-0002-0785-5410 https://orcid.org/0000-0002-1112-5912 |
Similar Items
-
Constraints on stable equilibria with fluctuation-induced (Casimir)
by: Rahi, Sahand Jamal, et al.
Published: (2011) -
Protein knot server: detection of knots in protein structures
by: Kolesov, Grigory, et al.
Published: (2012) -
8.592J / HST.452J Statistical Physics in Biology, Spring 2005
by: Mirny, Leonid, et al.
Published: (2005) -
Scattering theory approach to electrodynamic Casimir forces
by: Rahi, Sahand Jamal, et al.
Published: (2010) -
8.592 Statistical Physics in Biology, Spring 2003
by: Kardar, Mehran, et al.
Published: (2003)