The Cortical Signature of Alzheimer's Disease: Regionally Specific Cortical Thinning Relates to Symptom Severity in Very Mild to Mild AD Dementia and is Detectable in Asymptomatic Amyloid-Positive Individuals

Alzheimer's disease (AD) is associated with neurodegeneration in vulnerable limbic and heteromodal regions of the cerebral cortex, detectable in vivo using magnetic resonance imaging. It is not clear whether abnormalities of cortical anatomy in AD can be reliably measured across different subje...

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Main Authors: Dickerson, Bradford C., Bakkour, Akram, Salat, David H., Feczko, Eric, Pacheco, Jenni, Greve, Douglas N., Grodstein, Fran, Wright, Christopher I., Blacker, Deborah, Rosas, H. Diana, Sperling, Reisa A., Atri, Alireza, Growdon, John H., Hyman, Bradley T., Morris, John C., Fischl, Bruce, Buckner, Randy L.
其他作者: Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory
格式: 文件
语言:en_US
出版: Oxford University Press 2012
在线阅读:http://hdl.handle.net/1721.1/70979