The Cortical Signature of Alzheimer's Disease: Regionally Specific Cortical Thinning Relates to Symptom Severity in Very Mild to Mild AD Dementia and is Detectable in Asymptomatic Amyloid-Positive Individuals

The Cortical Signature of Alzheimer's Disease: Regionally Specific Cortical Thinning Relates to Symptom Severity in Very Mild to Mild AD Dementia and is Detectable in Asymptomatic Amyloid-Positive Individuals

Alzheimer's disease (AD) is associated with neurodegeneration in vulnerable limbic and heteromodal regions of the cerebral cortex, detectable in vivo using magnetic resonance imaging. It is not clear whether abnormalities of cortical anatomy in AD can be reliably measured across different subje...

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Bibliographic Details
Main Authors: Dickerson, Bradford C., Bakkour, Akram, Salat, David H., Feczko, Eric, Pacheco, Jenni, Greve, Douglas N., Grodstein, Fran, Wright, Christopher I., Blacker, Deborah, Rosas, H. Diana, Sperling, Reisa A., Atri, Alireza, Growdon, John H., Hyman, Bradley T., Morris, John C., Fischl, Bruce, Buckner, Randy L.
Other Authors: Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory
Format: Article
Language:en_US
Published: Oxford University Press 2012
Online Access:http://hdl.handle.net/1721.1/70979

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