DNA oligonucleotides with A, T, G or C opposite an abasic site: structure and dynamics

Abasic sites are common DNA lesions resulting from spontaneous depurination and excision of damaged nucleobases by DNA repair enzymes. However, the influence of the local sequence context on the structure of the abasic site and ultimately, its recognition and repair, remains elusive. In the present...

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Bibliographic Details
Main Authors: Dupradeau, François-Yves, Case, David A., Chen, Jingyang, Stubbe, JoAnne, Turner, Christopher J.
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: Oxford University Press (OUP) 2012
Online Access:http://hdl.handle.net/1721.1/71000
https://orcid.org/0000-0001-8076-4489