An intrinsically disordered yeast prion arrests the cell cycle by sequestering a spindle pole body component

An intrinsically disordered yeast prion arrests the cell cycle by sequestering a spindle pole body component

Intrinsically disordered proteins play causative roles in many human diseases. Their overexpression is toxic in many organisms, but the causes of toxicity are opaque. In this paper, we exploit yeast technologies to determine the root of toxicity for one such protein, the yeast prion Rnq1. This prote...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों:	Treusch, Sebastian, Lindquist, Susan
अन्य लेखक:	Massachusetts Institute of Technology. Department of Biology
स्वरूप:	लेख
भाषा:	en_US
प्रकाशित:	Rockefeller University Press, The 2012
ऑनलाइन पहुंच:	http://hdl.handle.net/1721.1/71750 https://orcid.org/0000-0003-1307-882X

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