Nanofluidic Concentration Device for Biomolecules Utilizing Ion Concentration Polarization: Theory, Fabrication, and Applications
This article was published as part of the From microfluidic application to nanofluidic phenomena issue
| Main Authors: | , , |
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| Other Authors: | |
| Format: | Article |
| Language: | en_US |
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Royal Society of Chemistry
2012
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| Online Access: | http://hdl.handle.net/1721.1/71836 https://orcid.org/0000-0001-7215-1439 |
| _version_ | 1826205551165440000 |
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| author | Kim, Sung Jae Song, Yong-Ak Han, Jongyoon |
| author2 | Massachusetts Institute of Technology. Department of Biological Engineering |
| author_facet | Massachusetts Institute of Technology. Department of Biological Engineering Kim, Sung Jae Song, Yong-Ak Han, Jongyoon |
| author_sort | Kim, Sung Jae |
| collection | MIT |
| description | This article was published as part of the From microfluidic application to nanofluidic phenomena issue |
| first_indexed | 2024-09-23T13:15:15Z |
| format | Article |
| id | mit-1721.1/71836 |
| institution | Massachusetts Institute of Technology |
| language | en_US |
| last_indexed | 2024-09-23T13:15:15Z |
| publishDate | 2012 |
| publisher | Royal Society of Chemistry |
| record_format | dspace |
| spelling | mit-1721.1/718362022-10-01T13:59:55Z Nanofluidic Concentration Device for Biomolecules Utilizing Ion Concentration Polarization: Theory, Fabrication, and Applications Kim, Sung Jae Song, Yong-Ak Han, Jongyoon Massachusetts Institute of Technology. Department of Biological Engineering Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science Han, Jongyoon Han, Jongyoon This article was published as part of the From microfluidic application to nanofluidic phenomena issue Recently, a new type of electrokinetic concentration devices has been developed in a microfluidic chip format, which allows efficient trapping and concentration of biomolecules by utilizing ion concentration polarization near nanofluidic structures. These devices have drawn much attention not only due to their potential application in biomolecule sensing, but also due to the rich scientific content related to ion concentration polarization, the underlying physical phenomenon for the operation of these electrokinetic concentration devices. This tutorial review provides an introduction to the scientific and engineering advances achieved, in-depth discussion about several interesting applications of these unique concentration devices, and their current limitations and challenges. National Science Foundation (U.S.) (CBET-0347348 & 0854026) National Institutes of Health (U.S.) (Grant EB005743) National Institutes of Health (U.S.) (Grant CA119402) National Institutes of Health (U.S.) (Grant P50-GM68762) 2012-07-26T14:48:43Z 2012-07-26T14:48:43Z 2010-01 2009-06 Article http://purl.org/eprint/type/JournalArticle 0306-0012 1460-4744 http://hdl.handle.net/1721.1/71836 Kim, Sung Jae, Yong-Ak Song, and Jongyoon Han. “Nanofluidic Concentration Devices for Biomolecules Utilizing Ion Concentration Polarization: Theory, Fabrication, and Applications.” Chemical Society Reviews 39.3 (2010): 912. Web. https://orcid.org/0000-0001-7215-1439 en_US http://dx.doi.org/10.1039/b822556g Chemical Society Reviews Creative Commons Attribution-Noncommercial-Share Alike 3.0 http://creativecommons.org/licenses/by-nc-sa/3.0/ application/pdf Royal Society of Chemistry PubMed Central |
| spellingShingle | Kim, Sung Jae Song, Yong-Ak Han, Jongyoon Nanofluidic Concentration Device for Biomolecules Utilizing Ion Concentration Polarization: Theory, Fabrication, and Applications |
| title | Nanofluidic Concentration Device for Biomolecules Utilizing Ion Concentration Polarization: Theory, Fabrication, and Applications |
| title_full | Nanofluidic Concentration Device for Biomolecules Utilizing Ion Concentration Polarization: Theory, Fabrication, and Applications |
| title_fullStr | Nanofluidic Concentration Device for Biomolecules Utilizing Ion Concentration Polarization: Theory, Fabrication, and Applications |
| title_full_unstemmed | Nanofluidic Concentration Device for Biomolecules Utilizing Ion Concentration Polarization: Theory, Fabrication, and Applications |
| title_short | Nanofluidic Concentration Device for Biomolecules Utilizing Ion Concentration Polarization: Theory, Fabrication, and Applications |
| title_sort | nanofluidic concentration device for biomolecules utilizing ion concentration polarization theory fabrication and applications |
| url | http://hdl.handle.net/1721.1/71836 https://orcid.org/0000-0001-7215-1439 |
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