Cortical GABAergic neurons: stretching it
In the cerebellum and basal ganglia, projection neurons are GABAergic; but in the cerebral cortex, there has been a historically strong dichotomy between glutamatergic projection neurons and GABAergic local circuit neurons. While this dichotomy is overwhelmingly valid, it is now clear that a small p...
| Main Authors: | , |
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| Other Authors: | |
| Format: | Article |
| Language: | en_US |
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Frontiers Research Foundation
2012
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| Online Access: | http://hdl.handle.net/1721.1/71895 https://orcid.org/0000-0002-6650-8785 |
| _version_ | 1826205752946065408 |
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| author | Rockland, Kathleen DeFelipe, Javier |
| author2 | Picower Institute for Learning and Memory |
| author_facet | Picower Institute for Learning and Memory Rockland, Kathleen DeFelipe, Javier |
| author_sort | Rockland, Kathleen |
| collection | MIT |
| description | In the cerebellum and basal ganglia, projection neurons are GABAergic; but in the cerebral cortex, there has been a historically strong dichotomy between glutamatergic projection neurons and GABAergic local circuit neurons. While this dichotomy is overwhelmingly valid, it is now clear that a small population of long-distance projecting GABAergic neurons occurs in primates, as well as in cats and rodents. Beyond their well-documented existence, however, the functional significance, ontogeny, and connectivity of this intriguing subpopulation remain obscure. |
| first_indexed | 2024-09-23T13:18:53Z |
| format | Article |
| id | mit-1721.1/71895 |
| institution | Massachusetts Institute of Technology |
| language | en_US |
| last_indexed | 2024-09-23T13:18:53Z |
| publishDate | 2012 |
| publisher | Frontiers Research Foundation |
| record_format | dspace |
| spelling | mit-1721.1/718952022-09-28T13:17:17Z Cortical GABAergic neurons: stretching it Rockland, Kathleen DeFelipe, Javier Picower Institute for Learning and Memory RIKEN-MIT Center for Neural Circuit Genetics Rockland, Kathleen Rockland, Kathleen In the cerebellum and basal ganglia, projection neurons are GABAergic; but in the cerebral cortex, there has been a historically strong dichotomy between glutamatergic projection neurons and GABAergic local circuit neurons. While this dichotomy is overwhelmingly valid, it is now clear that a small population of long-distance projecting GABAergic neurons occurs in primates, as well as in cats and rodents. Beyond their well-documented existence, however, the functional significance, ontogeny, and connectivity of this intriguing subpopulation remain obscure. 2012-07-30T19:04:13Z 2012-07-30T19:04:13Z 2012-05 2012-04 Article http://purl.org/eprint/type/JournalArticle 1662-5129 http://hdl.handle.net/1721.1/71895 Rockland, Kathleen S., and Javier DeFelipe. “Cortical GABAergic Neurons: Stretching It.” Frontiers in Neuroanatomy 6 (2012). https://orcid.org/0000-0002-6650-8785 en_US http://dx.doi.org/10.3389/fnana.2012.00016 Frontiers in Neuroanatomy Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use. application/pdf Frontiers Research Foundation Frontiers Research Foundation |
| spellingShingle | Rockland, Kathleen DeFelipe, Javier Cortical GABAergic neurons: stretching it |
| title | Cortical GABAergic neurons: stretching it |
| title_full | Cortical GABAergic neurons: stretching it |
| title_fullStr | Cortical GABAergic neurons: stretching it |
| title_full_unstemmed | Cortical GABAergic neurons: stretching it |
| title_short | Cortical GABAergic neurons: stretching it |
| title_sort | cortical gabaergic neurons stretching it |
| url | http://hdl.handle.net/1721.1/71895 https://orcid.org/0000-0002-6650-8785 |
| work_keys_str_mv | AT rocklandkathleen corticalgabaergicneuronsstretchingit AT defelipejavier corticalgabaergicneuronsstretchingit |