Pd-Catalyzed Cross-Coupling Reactions of Amides and Aryl Mesylates
A catalyst, based on a biarylphosphine ligand, for the Pd-catalyzed cross-coupling reactions of amides and aryl mesylates is described. This system allows an array of aryl and heteroaryl mesylates to be transformed into the corresponding N-aryl amides in moderate to excellent yields.
| Main Authors: | , , |
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| Other Authors: | |
| Format: | Article |
| Language: | en_US |
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American Chemical Society (ACS)
2012
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| Online Access: | http://hdl.handle.net/1721.1/71908 https://orcid.org/0000-0003-3875-4775 |
| _version_ | 1826201694853136384 |
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| author | Dooleweerdt, Karin Fors, Brett P. Buchwald, Stephen Leffler |
| author2 | Massachusetts Institute of Technology. Department of Chemistry |
| author_facet | Massachusetts Institute of Technology. Department of Chemistry Dooleweerdt, Karin Fors, Brett P. Buchwald, Stephen Leffler |
| author_sort | Dooleweerdt, Karin |
| collection | MIT |
| description | A catalyst, based on a biarylphosphine ligand, for the Pd-catalyzed cross-coupling reactions of amides and aryl mesylates is described. This system allows an array of aryl and heteroaryl mesylates to be transformed into the corresponding N-aryl amides in moderate to excellent yields. |
| first_indexed | 2024-09-23T11:55:17Z |
| format | Article |
| id | mit-1721.1/71908 |
| institution | Massachusetts Institute of Technology |
| language | en_US |
| last_indexed | 2024-09-23T11:55:17Z |
| publishDate | 2012 |
| publisher | American Chemical Society (ACS) |
| record_format | dspace |
| spelling | mit-1721.1/719082022-09-27T22:51:08Z Pd-Catalyzed Cross-Coupling Reactions of Amides and Aryl Mesylates Dooleweerdt, Karin Fors, Brett P. Buchwald, Stephen Leffler Massachusetts Institute of Technology. Department of Chemistry Buchwald, Stephen L. Dooleweerdt, Karin Fors, Brett P. Buchwald, Stephen Leffler A catalyst, based on a biarylphosphine ligand, for the Pd-catalyzed cross-coupling reactions of amides and aryl mesylates is described. This system allows an array of aryl and heteroaryl mesylates to be transformed into the corresponding N-aryl amides in moderate to excellent yields. National Institutes of Health (U.S.) (Grant Number GM-58160) Harvard University . BASF Advanced Research Initiative Merck Company Foundation Chemetall Nippon Chemical Industrial Co. Boehringer Ingelheim Pharmaceuticals. Fellowship Merck Company Foundation. Fellowship University of Aarhus. Department of Chemistry University of Aarhus. Interdisciplinary Nanoscience Centre National Science Foundation (Grant Number CHE 9808061) National Science Foundation (Grant Number DBI 9729592) 2012-07-31T13:39:58Z 2012-07-31T13:39:58Z 2010-04 2010-03 Article http://purl.org/eprint/type/JournalArticle 1523-7060 1523-7052 http://hdl.handle.net/1721.1/71908 Dooleweerdt, Karin, Brett P. Fors, and Stephen L. Buchwald. “Pd-Catalyzed Cross-Coupling Reactions of Amides and Aryl Mesylates.” Organic Letters 12.10 (2010): 2350–2353. https://orcid.org/0000-0003-3875-4775 en_US http://dx.doi.org/10.1021/ol100720x Organic Letters Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use. application/pdf American Chemical Society (ACS) PMC |
| spellingShingle | Dooleweerdt, Karin Fors, Brett P. Buchwald, Stephen Leffler Pd-Catalyzed Cross-Coupling Reactions of Amides and Aryl Mesylates |
| title | Pd-Catalyzed Cross-Coupling Reactions of Amides and Aryl Mesylates |
| title_full | Pd-Catalyzed Cross-Coupling Reactions of Amides and Aryl Mesylates |
| title_fullStr | Pd-Catalyzed Cross-Coupling Reactions of Amides and Aryl Mesylates |
| title_full_unstemmed | Pd-Catalyzed Cross-Coupling Reactions of Amides and Aryl Mesylates |
| title_short | Pd-Catalyzed Cross-Coupling Reactions of Amides and Aryl Mesylates |
| title_sort | pd catalyzed cross coupling reactions of amides and aryl mesylates |
| url | http://hdl.handle.net/1721.1/71908 https://orcid.org/0000-0003-3875-4775 |
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