Pd-Catalyzed Cross-Coupling Reactions of Amides and Aryl Mesylates

A catalyst, based on a biarylphosphine ligand, for the Pd-catalyzed cross-coupling reactions of amides and aryl mesylates is described. This system allows an array of aryl and heteroaryl mesylates to be transformed into the corresponding N-aryl amides in moderate to excellent yields.

Bibliographic Details
Main Authors: Dooleweerdt, Karin, Fors, Brett P., Buchwald, Stephen Leffler
Other Authors: Massachusetts Institute of Technology. Department of Chemistry
Format: Article
Language:en_US
Published: American Chemical Society (ACS) 2012
Online Access:http://hdl.handle.net/1721.1/71908
https://orcid.org/0000-0003-3875-4775