A role for nickel-iron cofactors in biological carbon monoxide and carbon dioxide utilization
Ni–Fe containing enzymes are involved in the biological utilization of carbon monoxide, carbon dioxide, and hydrogen. Interest in these enzymes has increased in recent years due to hydrogen fuel initiatives and concerns over development of new methods for CO2 sequestration. One Ni–Fe enzyme called c...
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| Format: | Article |
| Language: | en_US |
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Elsevier
2012
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| Online Access: | http://hdl.handle.net/1721.1/71970 https://orcid.org/0000-0001-5486-2755 |
| _version_ | 1826207956542160896 |
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| author | Kung, Yan Drennan, Catherine L |
| author2 | Massachusetts Institute of Technology. Department of Biology |
| author_facet | Massachusetts Institute of Technology. Department of Biology Kung, Yan Drennan, Catherine L |
| author_sort | Kung, Yan |
| collection | MIT |
| description | Ni–Fe containing enzymes are involved in the biological utilization of carbon monoxide, carbon dioxide, and hydrogen. Interest in these enzymes has increased in recent years due to hydrogen fuel initiatives and concerns over development of new methods for CO2 sequestration. One Ni–Fe enzyme called carbon monoxide dehydrogenase (CODH) is a key player in the global carbon cycle and carries out the interconversion of the environmental pollutant CO and the greenhouse gas CO[subscript 2]. The Ni–Fe center responsible for this important chemistry, the C-cluster, has been the source of much controversy, but several recent structural studies have helped to direct the field toward a unifying mechanism. Here we summarize the current state of understanding of this fascinating metallocluster. |
| first_indexed | 2024-09-23T13:57:36Z |
| format | Article |
| id | mit-1721.1/71970 |
| institution | Massachusetts Institute of Technology |
| language | en_US |
| last_indexed | 2024-09-23T13:57:36Z |
| publishDate | 2012 |
| publisher | Elsevier |
| record_format | dspace |
| spelling | mit-1721.1/719702024-03-21T20:16:11Z A role for nickel-iron cofactors in biological carbon monoxide and carbon dioxide utilization Kung, Yan Drennan, Catherine L Massachusetts Institute of Technology. Department of Biology Massachusetts Institute of Technology. Department of Chemistry Drennan, Catherine L. Kung, Yan Drennan, Catherine L. Ni–Fe containing enzymes are involved in the biological utilization of carbon monoxide, carbon dioxide, and hydrogen. Interest in these enzymes has increased in recent years due to hydrogen fuel initiatives and concerns over development of new methods for CO2 sequestration. One Ni–Fe enzyme called carbon monoxide dehydrogenase (CODH) is a key player in the global carbon cycle and carries out the interconversion of the environmental pollutant CO and the greenhouse gas CO[subscript 2]. The Ni–Fe center responsible for this important chemistry, the C-cluster, has been the source of much controversy, but several recent structural studies have helped to direct the field toward a unifying mechanism. Here we summarize the current state of understanding of this fascinating metallocluster. National Institutes of Health (U.S.) (GM69857) Massachusetts Institute of Technology. Energy Initiative Howard Hughes Medical Institute. Investigator 2012-08-03T13:06:32Z 2012-08-03T13:06:32Z 2010-12 Article http://purl.org/eprint/type/JournalArticle 1367-5931 http://hdl.handle.net/1721.1/71970 Kung, Yan, and Catherine L Drennan. “A Role for Nickel–iron Cofactors in Biological Carbon Monoxide and Carbon Dioxide Utilization.” Current Opinion in Chemical Biology 15.2 (2011): 276–283. https://orcid.org/0000-0001-5486-2755 en_US http://dx.doi.org/10.1016/j.cbpa.2010.11.005 Current Opinion in Chemical Biology Creative Commons Attribution-Noncommercial-Share Alike 3.0 http://creativecommons.org/licenses/by-nc-sa/3.0/ application/pdf Elsevier PMC |
| spellingShingle | Kung, Yan Drennan, Catherine L A role for nickel-iron cofactors in biological carbon monoxide and carbon dioxide utilization |
| title | A role for nickel-iron cofactors in biological carbon monoxide and carbon dioxide utilization |
| title_full | A role for nickel-iron cofactors in biological carbon monoxide and carbon dioxide utilization |
| title_fullStr | A role for nickel-iron cofactors in biological carbon monoxide and carbon dioxide utilization |
| title_full_unstemmed | A role for nickel-iron cofactors in biological carbon monoxide and carbon dioxide utilization |
| title_short | A role for nickel-iron cofactors in biological carbon monoxide and carbon dioxide utilization |
| title_sort | role for nickel iron cofactors in biological carbon monoxide and carbon dioxide utilization |
| url | http://hdl.handle.net/1721.1/71970 https://orcid.org/0000-0001-5486-2755 |
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