Subunit architecture of general transcription factor TFIIH
Structures of complete 10-subunit yeast TFIIH and of a nested set of subcomplexes, containing 5, 6, and 7 subunits, have been determined by electron microscopy (EM) and 3D reconstruction. Consistency among all the structures establishes the location of the “minimal core” subunits (Ssl1, Tfb1, Tfb2,...
Main Authors: | Brignole, Edward J., Gibbons, Brian J., Azubel, Maia, Murakami, Kenji, Voss, Neil R., Bushnell, David A., Asturias, Francisco J., Kornberg, Roger D. |
---|---|
Other Authors: | Massachusetts Institute of Technology. Department of Chemistry |
Format: | Article |
Language: | en_US |
Published: |
National Academy of Sciences
2012
|
Online Access: | http://hdl.handle.net/1721.1/72183 |
Similar Items
-
Subunit interactions in yeast transcription/repair factor TFIIH. Requirement for Tfb3 subunit in nucleotide excision repair.
by: Feaver, W, et al.
Published: (2000) -
Mutations in the general transcription factor TFIIH result in beta-thalassaemia in individuals with trichothiodystrophy.
by: Viprakasit, V, et al.
Published: (2001) -
Rad25p, a DNA helicase subunit of yeast transcription factor TFIIH, is required for promoter escape in vivo.
by: Ostapenko, D, et al.
Published: (2000) -
Mutations in a general transcription factor, TFIIH result in a novel unlinked form of beta thalassaemia in individuals with trichothiodystrophy.
by: Viprakasit, V, et al.
Published: (2001) -
C. elegans TFIIH subunit GTF-2H5/TTDA is a non-essential transcription factor indispensable for DNA repair
by: Karen L. Thijssen, et al.
Published: (2021-11-01)