Efficiency and Power as a Function of Sequence Coverage, SNP Array Density, and Imputation

Efficiency and Power as a Function of Sequence Coverage, SNP Array Density, and Imputation

High coverage whole genome sequencing provides near complete information about genetic variation. However, other technologies can be more efficient in some settings by (a) reducing redundant coverage within samples and (b) exploiting patterns of genetic variation across samples. To characterize as m...

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Bibliographic Details
Main Authors: Flannick, Jason, Korn, Joshua M., Fontanillas, Pierre, Grant, George B., Depristo, Mark A., Altshuler, David, Banks, Eric, 1976-
Other Authors: Harvard University--MIT Division of Health Sciences and Technology
Format: Article
Language:en_US
Published: Public Library of Science 2012
Online Access:http://hdl.handle.net/1721.1/72418
https://orcid.org/0000-0002-7250-4107

Internet

http://hdl.handle.net/1721.1/72418
https://orcid.org/0000-0002-7250-4107

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