Changes in the expression of the Alzheimer's disease-associated presenilin gene in drosophila heart leads to cardiac dysfunction

Changes in the expression of the Alzheimer's disease-associated presenilin gene in drosophila heart leads to cardiac dysfunction

Mutations in the presenilin genes cause the majority of early-onset familial Alzheimer’s disease. Recently, presenilin mutations have been identified in patients with dilated cardiomyopathy (DCM), a common cause of heart failure and the most prevalent diagnosis in cardiac transplantation patients...

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Bibliographic Details
Main Authors: Li, A., Zhou, C., Moore, J., Zhang, P., Tsai, Tsung-Han, Lee, Hsiang-Chieh, Romano, D. M., McKee, M. L., Schoenfeld, D. A., Serra, M. J., Raygor, K., Cantiello, H. F., Fujimoto, James G., Tanzi, R. E.
Other Authors: Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science
Format: Article
Language:en_US
Published: Bentham Science Publishers 2012
Online Access:http://hdl.handle.net/1721.1/72433
https://orcid.org/0000-0002-0828-4357
https://orcid.org/0000-0002-2976-6195

Internet

http://hdl.handle.net/1721.1/72433
https://orcid.org/0000-0002-0828-4357
https://orcid.org/0000-0002-2976-6195

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