Distinct Patterns of Expression and Evolution of Intronless and Intron-Containing Mammalian Genes

Distinct Patterns of Expression and Evolution of Intronless and Intron-Containing Mammalian Genes

Comparison of expression levels and breadth and evolutionary rates of intronless and intron-containing mammalian genes shows that intronless genes are expressed at lower levels, tend to be tissue specific, and evolve significantly faster than spliced genes. By contrast, monomorphic spliced genes tha...

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Bibliographic Details
Main Authors: Shabalina, Svetlana A., Ogurtsov, Aleksey Y., Spiridonov, Alexey Nikolaevich, Novichkov, Pavel S., Spiridonov, Nikolay A., Koonin, Eugene V.
Other Authors: Massachusetts Institute of Technology. Department of Mathematics
Format: Article
Language:en_US
Published: Oxford University Press on behalf of the Society for Molecular Biology and Evolution 2012
Online Access:http://hdl.handle.net/1721.1/72441

Internet

http://hdl.handle.net/1721.1/72441

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