Enhancing humoral responses to a malaria antigen with nanoparticle vaccines that expand Tfh cells and promote germinal center induction
For subunit vaccines, adjuvants play a key role in shaping immunological memory. Nanoparticle (NP) delivery systems for antigens and/or molecular danger signals are promising adjuvants capable of promoting both cellular and humoral immune responses, but in most cases the mechanisms of action of thes...
Main Authors: | Moon, James J., Suh, Heikyung, Li, Adrienne Victoria, Ockenhouse, Christian F., Yadava, Anjali, Irvine, Darrell J |
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Other Authors: | Massachusetts Institute of Technology. Department of Biological Engineering |
Format: | Article |
Language: | en_US |
Published: |
National Academy of Sciences
2012
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Online Access: | http://hdl.handle.net/1721.1/72495 https://orcid.org/0000-0003-0787-298X |
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