Reduced Activity of AMP-Activated Protein Kinase Protects against Genetic Models of Motor Neuron Disease

Reduced Activity of AMP-Activated Protein Kinase Protects against Genetic Models of Motor Neuron Disease

A growing body of research indicates that amyotrophic lateral sclerosis (ALS) patients and mouse models of ALS exhibit metabolic dysfunction. A subpopulation of ALS patients possesses higher levels of resting energy expenditure and lower fat-free mass compared to healthy controls. Similarly, two mut...

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Bibliographic Details
Main Authors: Lim, M. A., Selak, M. A., Xiang, Z., Krainc, Dimitri, Neve, Rachael L., Kraemer, B. C., Watts, J. L., Kalb, R. G.
Other Authors: Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences
Format: Article
Language:en_US
Published: Society for Neuroscience 2012
Online Access:http://hdl.handle.net/1721.1/72527
https://orcid.org/0000-0002-3854-5968

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