Regenerative Medicine: Learning from Past Examples
Regenerative medicine products have characteristically shown great therapeutic potential, but limited market success. Learning from the past attempts at capturing value is critical for new and emerging regenerative medicine therapies to define and evolve their business models as new therapies emerge...
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Format: | Article |
Language: | en_US |
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Mary Ann Liebert
2012
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Online Access: | http://hdl.handle.net/1721.1/72661 https://orcid.org/0000-0002-0828-535X |
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author | Couto, Daniela S. Perez-Breva, Luis Cooney, Charles L. |
author2 | Massachusetts Institute of Technology. Center for Biomedical Innovation |
author_facet | Massachusetts Institute of Technology. Center for Biomedical Innovation Couto, Daniela S. Perez-Breva, Luis Cooney, Charles L. |
author_sort | Couto, Daniela S. |
collection | MIT |
description | Regenerative medicine products have characteristically shown great therapeutic potential, but limited market success. Learning from the past attempts at capturing value is critical for new and emerging regenerative medicine therapies to define and evolve their business models as new therapies emerge and others mature. We propose a framework that analyzes technological developments along with alternative business models and illustrates how to use both strategically to map value capture by companies in regenerative medicine. We analyze how to balance flexibility of the supply chain and clarity in the regulatory pathway for each business model and propose the possible pathways of evolution between business models. We also drive analogies between cell-based therapies and other healthcare products such as biologicals and medical devices and suggest how to strategically evolve from these areas into the cell therapy space. |
first_indexed | 2024-09-23T11:27:03Z |
format | Article |
id | mit-1721.1/72661 |
institution | Massachusetts Institute of Technology |
language | en_US |
last_indexed | 2024-09-23T11:27:03Z |
publishDate | 2012 |
publisher | Mary Ann Liebert |
record_format | dspace |
spelling | mit-1721.1/726612022-09-27T19:34:58Z Regenerative Medicine: Learning from Past Examples Couto, Daniela S. Perez-Breva, Luis Cooney, Charles L. Massachusetts Institute of Technology. Center for Biomedical Innovation Massachusetts Institute of Technology. Department of Chemical Engineering Couto, Daniela S. Perez-Breva, Luis Cooney, Charles L. Regenerative medicine products have characteristically shown great therapeutic potential, but limited market success. Learning from the past attempts at capturing value is critical for new and emerging regenerative medicine therapies to define and evolve their business models as new therapies emerge and others mature. We propose a framework that analyzes technological developments along with alternative business models and illustrates how to use both strategically to map value capture by companies in regenerative medicine. We analyze how to balance flexibility of the supply chain and clarity in the regulatory pathway for each business model and propose the possible pathways of evolution between business models. We also drive analogies between cell-based therapies and other healthcare products such as biologicals and medical devices and suggest how to strategically evolve from these areas into the cell therapy space. MIT-Portugal Program. Bioengineering Focus Area (Fundação para a Ciência e a Tecnologia) Fundação para a Ciência e a Tecnologia. Scholarship MIT-Portugal Doctoral Program. Bioengineering (SFRH/BD/39444/2007) 2012-09-12T16:14:39Z 2012-09-12T16:14:39Z 2012-06 2011-11 Article http://purl.org/eprint/type/JournalArticle 1937-3341 1937-335X http://hdl.handle.net/1721.1/72661 Couto, Daniela S., Luis Perez-Breva, and Charles L. Cooney. “Regenerative Medicine: Learning from Past Examples.” Tissue Engineering Part A (2012): 120725085622009. Copyright © 2012 Mary Ann Liebert, Inc. publishers. https://orcid.org/0000-0002-0828-535X en_US http://dx.doi.org/10.1089/ten.TEA.2011.0639 Tissue Engineering. Part A Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use. application/pdf Mary Ann Liebert Mary Ann Leibert |
spellingShingle | Couto, Daniela S. Perez-Breva, Luis Cooney, Charles L. Regenerative Medicine: Learning from Past Examples |
title | Regenerative Medicine: Learning from Past Examples |
title_full | Regenerative Medicine: Learning from Past Examples |
title_fullStr | Regenerative Medicine: Learning from Past Examples |
title_full_unstemmed | Regenerative Medicine: Learning from Past Examples |
title_short | Regenerative Medicine: Learning from Past Examples |
title_sort | regenerative medicine learning from past examples |
url | http://hdl.handle.net/1721.1/72661 https://orcid.org/0000-0002-0828-535X |
work_keys_str_mv | AT coutodanielas regenerativemedicinelearningfrompastexamples AT perezbrevaluis regenerativemedicinelearningfrompastexamples AT cooneycharlesl regenerativemedicinelearningfrompastexamples |