Regenerative Medicine: Learning from Past Examples

Regenerative medicine products have characteristically shown great therapeutic potential, but limited market success. Learning from the past attempts at capturing value is critical for new and emerging regenerative medicine therapies to define and evolve their business models as new therapies emerge...

Full description

Bibliographic Details
Main Authors: Couto, Daniela S., Perez-Breva, Luis, Cooney, Charles L.
Other Authors: Massachusetts Institute of Technology. Center for Biomedical Innovation
Format: Article
Language:en_US
Published: Mary Ann Liebert 2012
Online Access:http://hdl.handle.net/1721.1/72661
https://orcid.org/0000-0002-0828-535X
_version_ 1826199866007617536
author Couto, Daniela S.
Perez-Breva, Luis
Cooney, Charles L.
author2 Massachusetts Institute of Technology. Center for Biomedical Innovation
author_facet Massachusetts Institute of Technology. Center for Biomedical Innovation
Couto, Daniela S.
Perez-Breva, Luis
Cooney, Charles L.
author_sort Couto, Daniela S.
collection MIT
description Regenerative medicine products have characteristically shown great therapeutic potential, but limited market success. Learning from the past attempts at capturing value is critical for new and emerging regenerative medicine therapies to define and evolve their business models as new therapies emerge and others mature. We propose a framework that analyzes technological developments along with alternative business models and illustrates how to use both strategically to map value capture by companies in regenerative medicine. We analyze how to balance flexibility of the supply chain and clarity in the regulatory pathway for each business model and propose the possible pathways of evolution between business models. We also drive analogies between cell-based therapies and other healthcare products such as biologicals and medical devices and suggest how to strategically evolve from these areas into the cell therapy space.
first_indexed 2024-09-23T11:27:03Z
format Article
id mit-1721.1/72661
institution Massachusetts Institute of Technology
language en_US
last_indexed 2024-09-23T11:27:03Z
publishDate 2012
publisher Mary Ann Liebert
record_format dspace
spelling mit-1721.1/726612022-09-27T19:34:58Z Regenerative Medicine: Learning from Past Examples Couto, Daniela S. Perez-Breva, Luis Cooney, Charles L. Massachusetts Institute of Technology. Center for Biomedical Innovation Massachusetts Institute of Technology. Department of Chemical Engineering Couto, Daniela S. Perez-Breva, Luis Cooney, Charles L. Regenerative medicine products have characteristically shown great therapeutic potential, but limited market success. Learning from the past attempts at capturing value is critical for new and emerging regenerative medicine therapies to define and evolve their business models as new therapies emerge and others mature. We propose a framework that analyzes technological developments along with alternative business models and illustrates how to use both strategically to map value capture by companies in regenerative medicine. We analyze how to balance flexibility of the supply chain and clarity in the regulatory pathway for each business model and propose the possible pathways of evolution between business models. We also drive analogies between cell-based therapies and other healthcare products such as biologicals and medical devices and suggest how to strategically evolve from these areas into the cell therapy space. MIT-Portugal Program. Bioengineering Focus Area (Fundação para a Ciência e a Tecnologia) Fundação para a Ciência e a Tecnologia. Scholarship MIT-Portugal Doctoral Program. Bioengineering (SFRH/BD/39444/2007) 2012-09-12T16:14:39Z 2012-09-12T16:14:39Z 2012-06 2011-11 Article http://purl.org/eprint/type/JournalArticle 1937-3341 1937-335X http://hdl.handle.net/1721.1/72661 Couto, Daniela S., Luis Perez-Breva, and Charles L. Cooney. “Regenerative Medicine: Learning from Past Examples.” Tissue Engineering Part A (2012): 120725085622009. Copyright © 2012 Mary Ann Liebert, Inc. publishers. https://orcid.org/0000-0002-0828-535X en_US http://dx.doi.org/10.1089/ten.TEA.2011.0639 Tissue Engineering. Part A Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use. application/pdf Mary Ann Liebert Mary Ann Leibert
spellingShingle Couto, Daniela S.
Perez-Breva, Luis
Cooney, Charles L.
Regenerative Medicine: Learning from Past Examples
title Regenerative Medicine: Learning from Past Examples
title_full Regenerative Medicine: Learning from Past Examples
title_fullStr Regenerative Medicine: Learning from Past Examples
title_full_unstemmed Regenerative Medicine: Learning from Past Examples
title_short Regenerative Medicine: Learning from Past Examples
title_sort regenerative medicine learning from past examples
url http://hdl.handle.net/1721.1/72661
https://orcid.org/0000-0002-0828-535X
work_keys_str_mv AT coutodanielas regenerativemedicinelearningfrompastexamples
AT perezbrevaluis regenerativemedicinelearningfrompastexamples
AT cooneycharlesl regenerativemedicinelearningfrompastexamples