Locating protein-coding sequences under selection for additional, overlapping functions in 29 mammalian genomes
The degeneracy of the genetic code allows protein-coding DNA and RNA sequences to simultaneously encode additional, overlapping functional elements. A sequence in which both protein-coding and additional overlapping functions have evolved under purifying selection should show increased evolutionary...
Main Authors: | Lin, Michael F., Kheradpour, Pouya, Mag Washietl, Stefan, Parker, Brian J., Pedersen, Jakob S., Kellis, Manolis |
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Other Authors: | Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory |
Format: | Article |
Language: | en_US |
Published: |
Cold Spring Harbor Laboratory Press
2012
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Online Access: | http://hdl.handle.net/1721.1/73052 |
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