Accelerating axonal growth promotes motor recovery after peripheral nerve injury in mice
Although peripheral nerves can regenerate after injury, proximal nerve injury in humans results in minimal restoration of motor function. One possible explanation for this is that injury-induced axonal growth is too slow. Heat shock protein 27 (Hsp27) is a regeneration-associated protein that accele...
Main Authors: | Gertler, Frank, Ma, Chi Him Eddie, Omura, Takao, Cobos, Enrique J., Latrémolière, Alban, Ghasemlou, Nader, Brenner, Gary J., Barrett, Lee, Sawada, Tomokazu, Gao, Fuying, Coppola, Giovanni, Costigan, Michael, Geschwind, Dan, Woolf, Clifford J., Van Veen, John |
---|---|
Other Authors: | Massachusetts Institute of Technology. Department of Biology |
Format: | Article |
Language: | en_US |
Published: |
American Society for Clinical Investigation
2012
|
Online Access: | http://hdl.handle.net/1721.1/73615 https://orcid.org/0000-0003-3214-4554 |
Similar Items
-
Repulsive axonal pathfinding requires the Ena/VASP family of actin regulatory proteins in vertebrates
by: Van Veen, John Edward
Published: (2012) -
A requirement for filopodia extension toward Slit during Robo-mediated axon repulsion
by: McConnell, Russell E., et al.
Published: (2017) -
Nervous Rac: DOCK7 Regulation of Axon Formation
by: Gertler, Frank, et al.
Published: (2014) -
Cytoskeletal Dynamics and Transport in Growth Cone Motility and Axon Guidance
by: Dent, Erik W., et al.
Published: (2014) -
Characterization of axonal transport defects in Drosophila Huntingtin mutants
by: Weiss, Kurt Richard, et al.
Published: (2016)