InAs(ZnCdS) Quantum Dots Optimized for Biological Imaging in the Near-Infrared
We present the synthesis of InAs quantum dots (QDs) with a ZnCdS shell with bright and stable emission in the near-infrared (NIR, 700−900 nm) region for biological imaging applications. We demonstrate how NIR QDs can image tumor vasculature in vivo at significantly deeper penetration depths and with...
Main Authors: | , , , , , , , |
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Other Authors: | |
Format: | Article |
Language: | en_US |
Published: |
American Chemical Society
2012
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Online Access: | http://hdl.handle.net/1721.1/73651 https://orcid.org/0000-0003-2220-4365 https://orcid.org/0000-0002-8277-5226 |
Summary: | We present the synthesis of InAs quantum dots (QDs) with a ZnCdS shell with bright and stable emission in the near-infrared (NIR, 700−900 nm) region for biological imaging applications. We demonstrate how NIR QDs can image tumor vasculature in vivo at significantly deeper penetration depths and with higher contrast than visible emitting CdSe(CdS) QDs. Targeted cellular labeling is also presented and may enable multiplexed and low autofluorescence cellular imaging. |
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