The genome of the green anole lizard and a comparative analysis with birds and mammals
The evolution of the amniotic egg was one of the great evolutionary innovations in the history of life, freeing vertebrates from an obligatory connection to water and thus permitting the conquest of terrestrial environments. Among amniotes, genome sequences are available for mammals and birds, but n...
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| Format: | Article |
| Language: | en_US |
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Nature Publishing Group
2012
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| Online Access: | http://hdl.handle.net/1721.1/74079 |
| _version_ | 1826199764354465792 |
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| author | Lander, Eric Steven |
| author2 | Massachusetts Institute of Technology. Department of Biology |
| author_facet | Massachusetts Institute of Technology. Department of Biology Lander, Eric Steven |
| author_sort | Lander, Eric Steven |
| collection | MIT |
| description | The evolution of the amniotic egg was one of the great evolutionary innovations in the history of life, freeing vertebrates from an obligatory connection to water and thus permitting the conquest of terrestrial environments. Among amniotes, genome sequences are available for mammals and birds, but not for non-avian reptiles. Here we report the genome sequence of the North American green anole lizard, Anolis carolinensis. We find that A. carolinensis microchromosomes are highly syntenic with chicken microchromosomes, yet do not exhibit the high GC and low repeat content that are characteristic of avian microchromosomes. Also, A. carolinensis mobile elements are very young and diverse—more so than in any other sequenced amniote genome. The GC content of this lizard genome is also unusual in its homogeneity, unlike the regionally variable GC content found in mammals and birds. We describe and assign sequence to the previously unknown A. carolinensis X chromosome. Comparative gene analysis shows that amniote egg proteins have evolved significantly more rapidly than other proteins. An anole phylogeny resolves basal branches to illuminate the history of their repeated adaptive radiations. |
| first_indexed | 2024-09-23T11:25:22Z |
| format | Article |
| id | mit-1721.1/74079 |
| institution | Massachusetts Institute of Technology |
| language | en_US |
| last_indexed | 2024-09-23T11:25:22Z |
| publishDate | 2012 |
| publisher | Nature Publishing Group |
| record_format | dspace |
| spelling | mit-1721.1/740792022-10-01T03:29:18Z The genome of the green anole lizard and a comparative analysis with birds and mammals Lander, Eric Steven Massachusetts Institute of Technology. Department of Biology Lander, Eric S. The evolution of the amniotic egg was one of the great evolutionary innovations in the history of life, freeing vertebrates from an obligatory connection to water and thus permitting the conquest of terrestrial environments. Among amniotes, genome sequences are available for mammals and birds, but not for non-avian reptiles. Here we report the genome sequence of the North American green anole lizard, Anolis carolinensis. We find that A. carolinensis microchromosomes are highly syntenic with chicken microchromosomes, yet do not exhibit the high GC and low repeat content that are characteristic of avian microchromosomes. Also, A. carolinensis mobile elements are very young and diverse—more so than in any other sequenced amniote genome. The GC content of this lizard genome is also unusual in its homogeneity, unlike the regionally variable GC content found in mammals and birds. We describe and assign sequence to the previously unknown A. carolinensis X chromosome. Comparative gene analysis shows that amniote egg proteins have evolved significantly more rapidly than other proteins. An anole phylogeny resolves basal branches to illuminate the history of their repeated adaptive radiations. National Science Foundation (U.S.) (NSF grant DEB-0920892) National Science Foundation (U.S.) (NSF grant DEB-0844624) National Human Genome Research Institute (U.S.) 2012-10-18T15:54:41Z 2012-10-18T15:54:41Z 2011-08 2011-04 Article http://purl.org/eprint/type/JournalArticle 0028-0836 1476-4687 http://hdl.handle.net/1721.1/74079 Alföldi, Jessica et al. “The Genome of the Green Anole Lizard and a Comparative Analysis with Birds and Mammals.” Nature 477.7366 (2011): 587–591. Web. en_US http://dx.doi.org/10.1038/nature10390 Nature Creative Commons Attribution-Noncommercial-Share Alike 3.0 http://creativecommons.org/licenses/by-nc-sa/3.0/ application/pdf Nature Publishing Group PMC |
| spellingShingle | Lander, Eric Steven The genome of the green anole lizard and a comparative analysis with birds and mammals |
| title | The genome of the green anole lizard and a comparative analysis with birds and mammals |
| title_full | The genome of the green anole lizard and a comparative analysis with birds and mammals |
| title_fullStr | The genome of the green anole lizard and a comparative analysis with birds and mammals |
| title_full_unstemmed | The genome of the green anole lizard and a comparative analysis with birds and mammals |
| title_short | The genome of the green anole lizard and a comparative analysis with birds and mammals |
| title_sort | genome of the green anole lizard and a comparative analysis with birds and mammals |
| url | http://hdl.handle.net/1721.1/74079 |
| work_keys_str_mv | AT landerericsteven thegenomeofthegreenanolelizardandacomparativeanalysiswithbirdsandmammals AT landerericsteven genomeofthegreenanolelizardandacomparativeanalysiswithbirdsandmammals |