lincRNAs act in the circuitry controlling pluripotency and differentiation
Although thousands of large intergenic non-coding RNAs (lincRNAs) have been identified in mammals, few have been functionally characterized, leading to debate about their biological role. To address this, we performed loss-of-function studies on most lincRNAs expressed in mouse embryonic stem (ES) c...
Main Authors: | Guttman, Mitchell, Donaghey, Julie, Carey, Bryce W., Garber, Manuel, Grenier, Jennifer K., Munson, Glen, Young, Geneva, Lucas, Anne Bergstom, Ach, Robert, Bruhn, Laurakay, Yang, Xiaoping, Amit, Ido, Meissner, Alexander, Regev, Aviv, Rinn, John L., Root, David E., Lander, Eric Steven |
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Other Authors: | Massachusetts Institute of Technology. Department of Biology |
Format: | Article |
Language: | en_US |
Published: |
Nature Publishing Group
2012
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Online Access: | http://hdl.handle.net/1721.1/74100 https://orcid.org/0000-0001-8567-2049 |
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