BAY61-3606 Affects the Viability of Colon Cancer Cells in a Genotype-Directed Manner

Background: K-RAS mutation poses a particularly difficult problem for cancer therapy. Activating mutations in K-RAS are common in cancers of the lung, pancreas, and colon and are associated with poor response to therapy. As such, targeted therapies that abrogate K-RAS-induced oncogenicity would be...

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Detaylı Bibliyografya
Asıl Yazarlar: Zhang, Tinghu, Kendall, Krystle R., Gray, Nathanael S., Haigis, Kevin M., Lau, Ken S., Lauffenburger, Douglas A
Diğer Yazarlar: Massachusetts Institute of Technology. Department of Biological Engineering
Materyal Türü: Makale
Dil:en_US
Baskı/Yayın Bilgisi: Public Library of Science 2012
Online Erişim:http://hdl.handle.net/1721.1/74526