Unconventional Ubiquitin Recognition by the Ubiquitin-Binding Motif within the Y-Family DNA Polymerases ι and Rev1

Unconventional Ubiquitin Recognition by the Ubiquitin-Binding Motif within the Y-Family DNA Polymerases ι and Rev1

Translesion synthesis is an essential cell survival strategy to promote replication after DNA damage. The accumulation of Y family polymerases (pol) ι and Rev1 at the stalled replication machinery is mediated by the ubiquitin-binding motifs (UBMs) of the polymerases and enhanced by PCNA monoubiquiti...

Full description

Bibliographic Details
Main Authors:	D'Souza, Sanjay Victor, Walker, Graham C., Bomar, Martha G., Bienko, Marzena, Dikic, Ivan, Zhou, Pei
Other Authors:	Massachusetts Institute of Technology. Department of Biology
Format:	Article
Language:	en_US
Published:	Elsevier 2012
Online Access:	http://hdl.handle.net/1721.1/74678 https://orcid.org/0000-0001-7243-8261

Similar Items

Ubiquitin-binding motif of human DNA polymerase eta is required for correct localization.
by: Sabbioneda, S, et al.
Published: (2009)

Ubiquitin-binding domains in Y-family polymerases regulate translesion synthesis.
by: Bienko, M, et al.
Published: (2005)

Biochemistry: Ubiquitin-binding domains in Y-family polymerases regulate translesion synthesis
by: Bienko, M, et al.
Published: (2005)

Editorial: Ubiquitin and Ubiquitin-Relative SUMO in DNA Damage Response
by: Kristijan Ramadan, et al.
Published: (2017-11-01)

Editorial: Ubiquitin and ubiquitin-rlative SUMO in DNA damage response
by: Ramadan, K, et al.
Published: (2017)

Structural basis for ubiquitin recognition by ubiquitin-binding zinc finger of FAAP20.
by: Aya Toma, et al.
Published: (2015-01-01)

Divergence of Legionella Effectors Reversing Conventional and Unconventional Ubiquitination
by: Tomoe Kitao, et al.
Published: (2020-08-01)

Myosin VI Contains a Compact Structural Motif that Binds to Ubiquitin Chains
by: Fahu He, et al.
Published: (2016-03-01)

The unusual UBZ domain of Saccharomyces cerevisiae polymerase η
by: Woodruff, Rachel V., et al.
Published: (2015)

The translesion DNA polymerases Pol ζ and Rev1 are activated independently of PCNA ubiquitination upon UV radiation in mutants of DNA polymerase δ.
by: Carine Tellier-Lebegue, et al.
Published: (2017-12-01)

Ubiquitin Interacting Motifs: Duality Between Structured and Disordered Motifs
by: Matteo Lambrughi, et al.
Published: (2021-06-01)

Structural Basis of Rev1-mediated Assembly of a Quaternary Vertebrate Translesion Polymerase Complex Consisting of Rev1, Heterodimeric Polymerase (Pol) κ, and Pol ζ
by: Wojtaszek, Jessica, et al.
Published: (2014)

Structural transformation of the tandem ubiquitin-interacting motifs in ataxin-3 and their cooperative interactions with ubiquitin chains.
by: Ai-Xin Song, et al.
Published: (2010-10-01)

Correction: The translesion DNA polymerases Pol ζ and Rev1 are activated independently of PCNA ubiquitination upon UV radiation in mutants of DNA polymerase δ.
by: Carine Tellier-Lebegue, et al.
Published: (2018-02-01)

The Roles of Ubiquitin-Binding Protein Shuttles in the Degradative Fate of Ubiquitinated Proteins in the Ubiquitin-Proteasome System and Autophagy
by: Katarzyna Zientara-Rytter, et al.
Published: (2019-01-01)

The ubiquitination landscape of the influenza A virus polymerase
by: Franziska Günl, et al.
Published: (2023-02-01)

A Ubiquitin-binding domain that binds a structural fold distinct from that of Ubiquitin
by: Lim, M, et al.
Published: (2019)

Generation and physiological roles of linear ubiquitin chains
by: Walczak Henning, et al.
Published: (2012-03-01)

NMR Structure and Dynamics of the C-Terminal Domain from Human Rev1 and Its Complex with Rev1 Interacting Region of DNA Polymerase η
by: Pozhidaeva, Alexandra, et al.
Published: (2014)

A Conserved LIR Motif in Connexins Mediates Ubiquitin-Independent Binding to LC3/GABARAP Proteins
by: Steve Catarino, et al.
Published: (2020-04-01)

Recognition of phosphodegron motifs in human cyclin E by the SCF(Fbw7) ubiquitin ligase.
by: Ye, X, et al.
Published: (2004)

ΙG Ι³ 219 and ΙG Ι³ 420 revisited
by: Georgia E. Malouchou
Published: (2019-07-01)

Identification and Characterization of Thermostable Y-Family DNA Polymerases η, ι, κ and Rev1 From a Lower Eukaryote, Thermomyces lanuginosus
by: Alexandra Vaisman, et al.
Published: (2021-11-01)

The Ubiquitin Conjugating Enzyme: An Important Ubiquitin Transfer Platform in Ubiquitin-Proteasome System
by: Weigang Liu, et al.
Published: (2020-04-01)

Rad5 participates in lesion bypass through its Rev1-binding and ubiquitin ligase domains, but not through its helicase function
by: Katarzyna H. Masłowska, et al.
Published: (2022-12-01)

Current methodologies in protein ubiquitination characterization: from ubiquitinated protein to ubiquitin chain architecture
by: Mingwei Sun, et al.
Published: (2022-08-01)

Lipid raft-dependent FcepsilonRI ubiquitination regulates receptor endocytosis through the action of ubiquitin binding adaptors.
by: Rosa Molfetta, et al.
Published: (2009-01-01)

Ubiquitin Pathways in Neurodegenerative Disease
by: Graham eAtkin, et al.
Published: (2014-07-01)

Ubiquitin receptor binding and signaling in primary human leukocytes
by: Vikas Saini, et al.
Published: (2010-11-01)

To Ubiquitinate or Not to Ubiquitinate: TRIM17 in Cell Life and Death
by: Meenakshi Basu-Shrivastava, et al.
Published: (2021-05-01)

Ubiquitination, Ubiquitin-like Modifiers, and Deubiquitination in Viral Infection
by: Isaacson, Marisa K., et al.
Published: (2014)

Hybrid Chains: A Collaboration of Ubiquitin and Ubiquitin-Like Modifiers Introducing Cross-Functionality to the Ubiquitin Code
by: David A. Pérez Berrocal, et al.
Published: (2020-01-01)

An E2-ubiquitin thioester-driven approach to identify substrates modified with ubiquitin and ubiquitin-like molecules
by: Gábor Bakos, et al.
Published: (2018-11-01)

Orthogonal ubiquitin transfer identifies ubiquitination substrates under differential control by the two ubiquitin activating enzymes
by: Xianpeng Liu, et al.
Published: (2017-01-01)

Proteasomal regulation of the mutagenic translesion DNA polymerase, Saccharomyces cerevisiae Rev1
by: Wiltrout, Mary Ellen, et al.
Published: (2015)

In silico elucidation of the recognition dynamics of ubiquitin.
by: Dong Long, et al.
Published: (2011-04-01)

In the moonlight: non-catalytic functions of ubiquitin and ubiquitin-like proteases
by: Marta Campos Alonso, et al.
Published: (2024-02-01)

Ubiquitination and Ubiquitin-Like Modifications in Multiple Myeloma: Biology and Therapy
by: Matthias Wirth, et al.
Published: (2020-12-01)

Contributions of Ubiquitin and Ubiquitination to Flaviviral Antagonism of Type I IFN
by: Erika Hay-McCullough, et al.
Published: (2021-04-01)

Targeted Regulation of Nuclear Lamins by Ubiquitin and Ubiquitin-Like Modifiers
by: Michael Blank
Published: (2020-05-01)