Primary monocytes regulate endothelial cell survival through secretion of Angiopoietin-1 and activation of endothelial Tie2

Objective—Monocyte recruitment and interaction with the endothelium is imperative to vascular recovery. Tie2 plays a key role in endothelial health and vascular remodeling. We studied monocyte-mediated Tie2/angiopoietin signaling following interaction of primary monocytes with endothelial cells and...

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Bibliographic Details
Main Authors: Schubert, Shai Y., Benarroch, Alejandro, Monter-Solans, Juan, Edelman, Elazer R.
Other Authors: Harvard University--MIT Division of Health Sciences and Technology
Format: Article
Language:en_US
Published: American Heart Association 2012
Online Access:http://hdl.handle.net/1721.1/75366
https://orcid.org/0000-0002-7832-7156