Efficient replication bypass of size-expanded DNA base pairs in bacterial cells
Author Manuscript 2012 September 06
| Main Authors: | , , , , , |
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| Other Authors: | |
| Format: | Article |
| Language: | en_US |
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Wiley Blackwell
2012
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| Online Access: | http://hdl.handle.net/1721.1/75427 https://orcid.org/0000-0001-6159-0778 https://orcid.org/0000-0002-2196-5691 |
| _version_ | 1826195398679592960 |
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| author | Delaney, James C. Gao, Jianmin Liu, Haibo Shrivastav, Nidhi Essigmann, John M. Kool, Eric T. |
| author2 | Massachusetts Institute of Technology. Department of Biological Engineering |
| author_facet | Massachusetts Institute of Technology. Department of Biological Engineering Delaney, James C. Gao, Jianmin Liu, Haibo Shrivastav, Nidhi Essigmann, John M. Kool, Eric T. |
| author_sort | Delaney, James C. |
| collection | MIT |
| description | Author Manuscript 2012 September 06 |
| first_indexed | 2024-09-23T10:12:02Z |
| format | Article |
| id | mit-1721.1/75427 |
| institution | Massachusetts Institute of Technology |
| language | en_US |
| last_indexed | 2024-09-23T10:12:02Z |
| publishDate | 2012 |
| publisher | Wiley Blackwell |
| record_format | dspace |
| spelling | mit-1721.1/754272022-09-30T19:32:52Z Efficient replication bypass of size-expanded DNA base pairs in bacterial cells Delaney, James C. Gao, Jianmin Liu, Haibo Shrivastav, Nidhi Essigmann, John M. Kool, Eric T. Massachusetts Institute of Technology. Department of Biological Engineering Massachusetts Institute of Technology. Department of Chemistry Delaney, James C. Shrivastav, Nidhi Essigmann, John M. Author Manuscript 2012 September 06 Supersize me! Size-expanded DNA bases (xDNA) are able to encode natural DNA sequences in replication. In vitro experiments with a DNA polymerase show nucleotide incorporation opposite the xDNA bases with correct pairing. In vivo experiments using E. coli show that two xDNA bases (xA and xC, see picture) encode the correct replication partners. National Institutes of Health (U.S.) (CA80024) National Institutes of Health (U.S.) (GM63587) Stanford Graduate Fellowship 2012-12-12T18:48:18Z 2012-12-12T18:48:18Z 2009-05 Article http://purl.org/eprint/type/JournalArticle 0044-8249 1521-3757 http://hdl.handle.net/1721.1/75427 Delaney, James C. et al. “Efficient Replication Bypass of Size-Expanded DNA Base Pairs in Bacterial Cells.” Angewandte Chemie International Edition 48.25 (2009): 4524–4527. https://orcid.org/0000-0001-6159-0778 https://orcid.org/0000-0002-2196-5691 en_US http://dx.doi.org/10.1002/anie.200805683 Angewandte Chemie Creative Commons Attribution-Noncommercial-Share Alike 3.0 http://creativecommons.org/licenses/by-nc-sa/3.0/ application/pdf Wiley Blackwell PMC |
| spellingShingle | Delaney, James C. Gao, Jianmin Liu, Haibo Shrivastav, Nidhi Essigmann, John M. Kool, Eric T. Efficient replication bypass of size-expanded DNA base pairs in bacterial cells |
| title | Efficient replication bypass of size-expanded DNA base pairs in bacterial cells |
| title_full | Efficient replication bypass of size-expanded DNA base pairs in bacterial cells |
| title_fullStr | Efficient replication bypass of size-expanded DNA base pairs in bacterial cells |
| title_full_unstemmed | Efficient replication bypass of size-expanded DNA base pairs in bacterial cells |
| title_short | Efficient replication bypass of size-expanded DNA base pairs in bacterial cells |
| title_sort | efficient replication bypass of size expanded dna base pairs in bacterial cells |
| url | http://hdl.handle.net/1721.1/75427 https://orcid.org/0000-0001-6159-0778 https://orcid.org/0000-0002-2196-5691 |
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