BCL-2 family genetic profiling reveals microenvironment-specific determinants of chemotherapeutic response

BCL-2 family genetic profiling reveals microenvironment-specific determinants of chemotherapeutic response

The Bcl-2 family encompasses a diverse set of apoptotic regulators that are dynamically activated in response to various cell-intrinsic and -extrinsic stimuli. An extensive variety of cell culture experiments have identified effects of growth factors, cytokines, and drugs on Bcl-2 family functions,...

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Bibliographic Details
Main Authors:	Gilbert, Luke Andrew, Meacham, Corbin Elizabeth, Jiang, Hai, Hemann, Michael, Pritchard, Justin R., Shingleton, Jennifer R., Lauffenburger, Douglas A
Other Authors:	Massachusetts Institute of Technology. Department of Biological Engineering
Format:	Article
Language:	en_US
Published:	American Association for Cancer Research 2013
Online Access:	http://hdl.handle.net/1721.1/76213

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