ANALYSIS OF SITE-SPECIFIC MUTATIONS ON EGFRVIII PHOSPHOTYROSINE SIGNALING NETWORK IDENTIFIES DETERMINANTS GOVERNING U87MG GLIOBLASTOMA CELL GROWTH

ANALYSIS OF SITE-SPECIFIC MUTATIONS ON EGFRVIII PHOSPHOTYROSINE SIGNALING NETWORK IDENTIFIES DETERMINANTS GOVERNING U87MG GLIOBLASTOMA CELL GROWTH

available in PMC 2012 March 1.

Bibliographic Details
Main Authors:	Huang, Paul H., Miraldi, Emily Rae, Xu, Alexander M., Kundukulam, Vibin Anto, Flynn, Ryan A., Cavenee, Webster K., Furnari, Frank B., White, Forest M., Del Rosario, Amanda M
Other Authors:	Massachusetts Institute of Technology. Computational and Systems Biology Program
Format:	Article
Language:	en_US
Published:	Royal Society of Chemistry 2013
Online Access:	http://hdl.handle.net/1721.1/76321 https://orcid.org/0000-0002-1545-1651 https://orcid.org/0000-0001-5013-0442

Similar Items

Societal and technical issues in the industrial development of Saudi Arabia and Egypt
by: Kundukulam, Vibin A. (Vibin Anto)
Published: (2012)

Toward quantitative phosphotyrosine profiling in vivo
by: Johnson, Hannah, et al.
Published: (2014)

Effects of Aptamer to U87-EGFRvIII Cells on the Proliferation, Radiosensitivity, and Radiotherapy of Glioblastoma Cells
by: Xingmei Zhang, et al.
Published: (2023-09-01)

Effects of Aptamer to U87-EGFRvIII Cells on the Proliferation, Radiosensitivity, and Radiotherapy of Glioblastoma Cells
by: Xingmei Zhang, et al.
Published: (2018-03-01)

Current therapeutic advances targeting EGFR and EGFRvIII in glioblastoma
by: Emily ePadfield, et al.
Published: (2015-01-01)

Interleukin-13 receptor alpha 2 cooperates with EGFRvIII signaling to promote glioblastoma multiforme
by: Jennifer P. Newman, et al.
Published: (2017-12-01)

The natural history of EGFR and EGFRvIII in glioblastoma patients
by: Shi Weiming, et al.
Published: (2005-10-01)

Expression of EGFRvIII in Glioblastoma: Prognostic Significance Revisited
by: Nicola Montano, et al.
Published: (2011-12-01)

TNFα inhibitor C87 sensitizes EGFRvIII transfected glioblastoma cells to gefitinib by a concurrent blockade of TNFα signaling
by: Li Ma, et al.
Published: (2019-09-01)

Molecular network analysis of phosphotyrosine and lipid metabolism in hepatic PTP1b deletion mice
by: Miraldi, Emily Rae, et al.
Published: (2014)

GZ17-6.02 Inhibits the Growth of EGFRvIII+ Glioblastoma
by: Justin Choi, et al.
Published: (2022-04-01)

Quantitative analysis of the EGFRvIII mutant receptor signaling networks in Glioblastoma
by: Huang, Hua Ming Paul
Published: (2009)

Exosome Proteome of U-87MG Glioblastoma Cells
by: Sohyun Chun, et al.
Published: (2016-12-01)

Modeling HER2 effects on cell behavior from mass spectrometry phosphotyrosine data.
by: Neil Kumar, et al.
Published: (2007-01-01)

An integrated comparative phosphoproteomic and bioinformatic approach reveals a novel class of MPM-2 motifs upregulated in EGFRvIII-expressing Glioblastoma Cells
by: Naegle, Kristen Marie, et al.
Published: (2011)

Phosphotyrosine Profiling of NSCLC Cells in Response to EGF and HGF Reveals Network Specific Mediators of Invasion
by: Johnson, Hannah, et al.
Published: (2014)

Phenotypical Flexibility of the EGFRvIII-Positive Glioblastoma Cell Line and the Multidirectional Influence of TGFβ and EGF on These Cells—EGFRvIII Appears as a Weak Oncogene
by: Aneta Włodarczyk, et al.
Published: (2022-10-01)

Specificity, Safety, Efficacy of EGFRvIII-Retargeted Oncolytic HSV for Xenotransplanted Human Glioblastoma
by: Irene Appolloni, et al.
Published: (2021-08-01)

A novel small molecule that selectively inhibits glioblastoma cells expressing EGFRvIII
by: Oberlies Nicholas H, et al.
Published: (2007-04-01)

Novel high‐affinity EGFRvIII‐specific chimeric antigen receptor T cells effectively eliminate human glioblastoma
by: Rebecca C Abbott, et al.
Published: (2021-01-01)

Novel high‐affinity EGFRvIII‐specific chimeric antigen receptor T cells effectively eliminate human glioblastoma
by: Rebecca C Abbott, et al.
Published: (2021-01-01)

249 Vascular normalization improves the delivery and efficacy of EGFRvIII-CAR-T cells in mouse glioblastoma
by: Dai Fukumura, et al.
Published: (2023-11-01)

IGFBP3 induced by the TGF-β/EGFRvIII transactivation contributes to the malignant phenotype of glioblastoma
by: Xuehua Zhang, et al.
Published: (2023-05-01)

Chemosensitization of U-87 MG Glioblastoma Cells by Neobavaisoflavone towards Doxorubicin and Etoposide
by: Mateusz Maszczyk, et al.
Published: (2022-05-01)

Development of an EGFRvIII specific recombinant antibody
by: Li Gordon, et al.
Published: (2010-10-01)

High‐fat diet in a mouse insulin‐resistant model induces widespread rewiring of the phosphotyrosine signaling network
by: Dittmann, Antje, et al.
Published: (2020)

PD1 Expression in EGFRvIII-Directed CAR T Cell Infusion Product for Glioblastoma Is Associated with Clinical Response
by: Oliver Y. Tang, et al.
Published: (2022-05-01)

Simultaneous detection of EGFR amplification and EGFRvIII variant using digital PCR-based method in glioblastoma
by: Maxime Fontanilles, et al.
Published: (2020-04-01)

Afatinib and Temozolomide combination inhibits tumorigenesis by targeting EGFRvIII-cMet signaling in glioblastoma cells
by: Raghupathy Vengoji, et al.
Published: (2019-06-01)

Human EGFRvIII chimeric antigen receptor T cells demonstrate favorable safety profile and curative responses in orthotopic glioblastoma
by: Rebecca C Abbott, et al.
Published: (2023-01-01)

Ceramide Is Involved in Temozolomide Resistance in Human Glioblastoma U87MG Overexpressing EGFR
by: Rosaria Bassi, et al.
Published: (2023-10-01)

Inhibition of growth of U87MG human glioblastoma cells by Usnea longissima Ach.
by: BUGRAHAN EMSEN, et al.

Phosphotyrosine Signaling Analysis in Human Tumors Is Confounded by Systemic Ischemia-Driven Artifacts and Intra-Specimen Heterogeneity
by: Slebos, R. J. C., et al.
Published: (2017)

G2 checkpoint targeting via Wee1 inhibition radiosensitizes EGFRvIII-positive glioblastoma cells
by: Meryem H. Cetin, et al.
Published: (2023-01-01)

High‐fat diet in a mouse insulin‐resistant model induces widespread rewiring of the phosphotyrosine signaling network
by: Antje Dittmann, et al.
Published: (2019-08-01)

Phosphotyrosine recognition domains: the typical, the atypical and the versatile.
by: Kaneko, T, et al.
Published: (2012)

Biomolecules to Biomarkers? U87MG Marker Evaluation on the Path towards Glioblastoma Multiforme Pathogenesis
by: Markéta Pokorná, et al.
Published: (2024-01-01)

Angiogenesis inhibition on glioblastoma multiforme cell lines (U-87 MG and T98G) by AT-101
by: Burcu Cakar, et al.
Published: (2018-08-01)

In Vitro Radiosensitizing Effects of Temozolomide on U87MG Cell Lines of Human Glioblastoma Multiforme
by: Samira Borhani, et al.
Published: (2017-05-01)

Expression of the Apoptotic Proteins in Glioblastoma U87-MG Cell Line Treated by Botulinum Toxin
by: Mona Farhadi, et al.
Published: (2020-07-01)