Enhancing solubility of deoxyxylulose phosphate pathway enzymes for microbial isoprenoid production

Background: Recombinant proteins are routinely overexpressed in metabolic engineering. It is well known that some over-expressed heterologous recombinant enzymes are insoluble with little or no enzymatic activity. This study examined the solubility of over-expressed homologous enzymes of the deoxyx...

Full description

Bibliographic Details
Main Authors: Zhou, Kang, Zou, Ruiyang, Stephanopoulos, Gregory, Too, Heng-Phon
Other Authors: Massachusetts Institute of Technology. Department of Chemical Engineering
Format: Article
Language:English
Published: BioMed Central Ltd. 2013
Online Access:http://hdl.handle.net/1721.1/76588
https://orcid.org/0000-0001-6909-4568