Preferential targeting of co-evolving Gag residues in long-term non progressors

Background: A recent analysis of mutational patterns within Gag revealed independently evolving groups of residues (termed sectors) whose mutations are collectively coordinated. Of these sectors, sector 3 is the least tolerant of multiple simultaneous mutations and therefore is proposed to be the...

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Bibliographic Details
Main Authors: Sunshine, J., Shekhar, Karthik, Heckerman, David, Frahm, Nicole, Chakraborty, Arup K
Other Authors: Massachusetts Institute of Technology. Institute for Medical Engineering & Science
Format: Article
Language:en_US
Published: Biomed Central Ltd. 2013
Online Access:http://hdl.handle.net/1721.1/76619
https://orcid.org/0000-0003-1268-9602