Cholesterol-tethered platinum II-based supramolecular nanoparticle increases antitumor efficacy and reduces nephrotoxicity

Cholesterol-tethered platinum II-based supramolecular nanoparticle increases antitumor efficacy and reduces nephrotoxicity

Nanoscale drug delivery vehicles have been harnessed extensively as carriers for cancer chemotherapeutics. However, traditional pharmaceutical approaches for nanoformulation have been a challenge with molecules that exhibit incompatible physicochemical properties, such as platinum-based chemotherape...

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Bibliographic Details
Main Authors: Sengupta, Poulomi, Basu, Sudipta, Soni, Shivani, Pandey, Ambarish, Roy, Bhaskar, Oh, Michael S., Chin, Kenneth T., Paraskar, Abhimanyu S., Sarangi, Sasmit, Connor, Yamicia D., Sabbisetti, Venkata, Kopparam, Jawahar, Kulkarni, Ashish, Muto, Katherine, Amarasiriwardena, Chitra, Jayawardene, Innocent, Lupoli, Nicola, Dinulescu, Daniela M., Bonventre, Joseph V., Mashelkar, Raghunath Anant, Sengupta, Shiladitya
Other Authors: Harvard University--MIT Division of Health Sciences and Technology
Format: Article
Language:en_US
Published: National Academy of Sciences (U.S.) 2013
Online Access:http://hdl.handle.net/1721.1/76785
https://orcid.org/0000-0002-5436-389X

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