Adaptive Evolution and the Birth of CTCF Binding Sites in the Drosophila Genome

Adaptive Evolution and the Birth of CTCF Binding Sites in the Drosophila Genome

Changes in the physical interaction between cis-regulatory DNA sequences and proteins drive the evolution of gene expression. However, it has proven difficult to accurately quantify evolutionary rates of such binding change or to estimate the relative effects of selection and drift in shaping the bi...

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Bibliographic Details
Main Authors: Chen, Sidi, Ni, Xiaochun, Long, Manyuan, Negre, Nicolas, Zhang, Yong E., White, Kevin P.
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: Public Library of Science 2013
Online Access:http://hdl.handle.net/1721.1/77185

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http://hdl.handle.net/1721.1/77185

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