Adaptive Evolution and the Birth of CTCF Binding Sites in the Drosophila Genome
Changes in the physical interaction between cis-regulatory DNA sequences and proteins drive the evolution of gene expression. However, it has proven difficult to accurately quantify evolutionary rates of such binding change or to estimate the relative effects of selection and drift in shaping the bi...
| Main Authors: | , , , , , |
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| Other Authors: | |
| Format: | Article |
| Language: | en_US |
| Published: |
Public Library of Science
2013
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| Online Access: | http://hdl.handle.net/1721.1/77185 |