The protein phosphatase 2A functions in the spindle position checkpoint by regulating the checkpoint kinase Kin4

In budding yeast, a surveillance mechanism known as the spindle position checkpoint (SPOC) ensures accurate genome partitioning. In the event of spindle misposition, the checkpoint delays exit from mitosis by restraining the activity of the mitotic exit network (MEN). To date, the only component of...

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Bibliographic Details
Main Authors: Chan, Leon Y., Amon, Angelika B
Other Authors: Koch Institute for Integrative Cancer Research at MIT
Format: Article
Language:en_US
Published: Cold Spring Harbor Laboratory Press 2013
Online Access:http://hdl.handle.net/1721.1/77594
https://orcid.org/0000-0001-9837-0314