Dynamic Modeling of Cell Migration and Spreading Behaviors on Fibronectin Coated Planar Substrates and Micropatterned Geometries
An integrative cell migration model incorporating focal adhesion (FA) dynamics, cytoskeleton and nucleus remodeling, actin motor activity, and lamellipodia protrusion is developed for predicting cell spreading and migration behaviors. This work is motivated by two experimental works: (1) cell migrat...
Main Authors: | Kim, Min-Cheol, Kamm, Roger Dale, Neal, Devin M, Asada, Haruhiko |
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Other Authors: | Massachusetts Institute of Technology. Department of Mechanical Engineering |
Format: | Article |
Language: | en_US |
Published: |
Public Library of Science
2013
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Online Access: | http://hdl.handle.net/1721.1/78342 https://orcid.org/0000-0001-6649-9463 https://orcid.org/0000-0003-3155-6223 https://orcid.org/0000-0002-7232-304X |
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