Dynamic Modeling of Cell Migration and Spreading Behaviors on Fibronectin Coated Planar Substrates and Micropatterned Geometries

An integrative cell migration model incorporating focal adhesion (FA) dynamics, cytoskeleton and nucleus remodeling, actin motor activity, and lamellipodia protrusion is developed for predicting cell spreading and migration behaviors. This work is motivated by two experimental works: (1) cell migrat...

Full description

Bibliographic Details
Main Authors: Kim, Min-Cheol, Kamm, Roger Dale, Neal, Devin M, Asada, Haruhiko
Other Authors: Massachusetts Institute of Technology. Department of Mechanical Engineering
Format: Article
Language:en_US
Published: Public Library of Science 2013
Online Access:http://hdl.handle.net/1721.1/78342
https://orcid.org/0000-0001-6649-9463
https://orcid.org/0000-0003-3155-6223
https://orcid.org/0000-0002-7232-304X

Similar Items