Properties of cell death models calibrated and compared using Bayesian approaches
Using models to simulate and analyze biological networks requires principled approaches to parameter estimation and model discrimination. We use Bayesian and Monte Carlo methods to recover the full probability distributions of free parameters (initial protein concentrations and rate constants) for m...
Main Authors: | Eydgahi, Hoda, Chen, William W., Muhlich, Jeremy L., Vitkup, Dennis, Tsitsiklis, John N., Sorger, Peter K. |
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Other Authors: | Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science |
Format: | Article |
Language: | en_US |
Published: |
Nature Publishing Group
2013
|
Online Access: | http://hdl.handle.net/1721.1/78587 https://orcid.org/0000-0003-2658-8239 |
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