Properties of cell death models calibrated and compared using Bayesian approaches

Using models to simulate and analyze biological networks requires principled approaches to parameter estimation and model discrimination. We use Bayesian and Monte Carlo methods to recover the full probability distributions of free parameters (initial protein concentrations and rate constants) for m...

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Bibliographic Details
Main Authors: Eydgahi, Hoda, Chen, William W., Muhlich, Jeremy L., Vitkup, Dennis, Tsitsiklis, John N., Sorger, Peter K.
Other Authors: Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science
Format: Article
Language:en_US
Published: Nature Publishing Group 2013
Online Access:http://hdl.handle.net/1721.1/78587
https://orcid.org/0000-0003-2658-8239

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