MICU2, a Paralog of MICU1, Resides within the Mitochondrial Uniporter Complex to Regulate Calcium Handling

MICU2, a Paralog of MICU1, Resides within the Mitochondrial Uniporter Complex to Regulate Calcium Handling

Mitochondrial calcium uptake is present in nearly all vertebrate tissues and is believed to be critical in shaping calcium signaling, regulating ATP synthesis and controlling cell death. Calcium uptake occurs through a channel called the uniporter that resides in the inner mitochondrial membrane. Re...

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Bibliographic Details
Main Authors: Plovanich, Molly, Bogorad, Roman, Sancak, Yasemin, Kamer, Kimberli J., Strittmatter, Laura, Li, Andrew A., Girgis, Hany S., Kuchimanchi, Satya, Groot, Jack De, Speciner, Lauren, Taneja, Nathan, OShea, Jonathan, Kotelianski, Victor E., Mootha, Vamsi K.
Other Authors: Koch Institute for Integrative Cancer Research at MIT
Format: Article
Language:en_US
Published: Public Library of Science 2013
Online Access:http://hdl.handle.net/1721.1/78642

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