Robust and economical multi-sample, multi-wavelength UV/vis absorption and fluorescence detector for biological and chemical contamination
We present a portable multi-channel, multi-sample UV/vis absorption and fluorescence detection device, which has no moving parts, can operate wirelessly and on batteries, interfaces with smart mobile phones or tablets, and has the sensitivity of commercial instruments costing an order of magnitude m...
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| Format: | Article |
| Language: | en_US |
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American Institute of Physics (AIP)
2013
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| Online Access: | http://hdl.handle.net/1721.1/79117 https://orcid.org/0000-0002-5048-4109 |
| _version_ | 1826198374172327936 |
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| author | Lu, Peter J. Macarthur, James B. Sims, Peter A. Ma, Hongshen Slocum, Alexander H. Hoehl, Melanie Margarete |
| author2 | Harvard University--MIT Division of Health Sciences and Technology |
| author_facet | Harvard University--MIT Division of Health Sciences and Technology Lu, Peter J. Macarthur, James B. Sims, Peter A. Ma, Hongshen Slocum, Alexander H. Hoehl, Melanie Margarete |
| author_sort | Lu, Peter J. |
| collection | MIT |
| description | We present a portable multi-channel, multi-sample UV/vis absorption and fluorescence detection device, which has no moving parts, can operate wirelessly and on batteries, interfaces with smart mobile phones or tablets, and has the sensitivity of commercial instruments costing an order of magnitude more. We use UV absorption to measure the concentration of ethylene glycol in water solutions at all levels above those deemed unsafe by the United States Food and Drug Administration; in addition we use fluorescence to measure the concentration of d-glucose. Both wavelengths can be used concurrently to increase measurement robustness and increase detection sensitivity. Our small robust economical device can be deployed in the absence of laboratory infrastructure, and therefore may find applications immediately following natural disasters, and in more general deployment for much broader-based testing of food, agricultural and household products to prevent outbreaks of poisoning and disease. |
| first_indexed | 2024-09-23T11:03:52Z |
| format | Article |
| id | mit-1721.1/79117 |
| institution | Massachusetts Institute of Technology |
| language | en_US |
| last_indexed | 2024-09-23T11:03:52Z |
| publishDate | 2013 |
| publisher | American Institute of Physics (AIP) |
| record_format | dspace |
| spelling | mit-1721.1/791172022-10-01T00:54:38Z Robust and economical multi-sample, multi-wavelength UV/vis absorption and fluorescence detector for biological and chemical contamination Lu, Peter J. Macarthur, James B. Sims, Peter A. Ma, Hongshen Slocum, Alexander H. Hoehl, Melanie Margarete Harvard University--MIT Division of Health Sciences and Technology Massachusetts Institute of Technology. Department of Mechanical Engineering Hoehl, Melanie Margarete Ma, Hongshen Slocum, Alexander H. We present a portable multi-channel, multi-sample UV/vis absorption and fluorescence detection device, which has no moving parts, can operate wirelessly and on batteries, interfaces with smart mobile phones or tablets, and has the sensitivity of commercial instruments costing an order of magnitude more. We use UV absorption to measure the concentration of ethylene glycol in water solutions at all levels above those deemed unsafe by the United States Food and Drug Administration; in addition we use fluorescence to measure the concentration of d-glucose. Both wavelengths can be used concurrently to increase measurement robustness and increase detection sensitivity. Our small robust economical device can be deployed in the absence of laboratory infrastructure, and therefore may find applications immediately following natural disasters, and in more general deployment for much broader-based testing of food, agricultural and household products to prevent outbreaks of poisoning and disease. Center for Integration of Medicine and Innovative Technology Legatum Center for Development & Entrepreneurship (Massachusetts Institute of Technology) NVIDIA Corporation (Professor Partnership Program) 2013-06-17T13:52:36Z 2013-06-17T13:52:36Z 2012-07 2012-04 Article http://purl.org/eprint/type/JournalArticle 2158-3226 http://hdl.handle.net/1721.1/79117 Lu, Peter J., Melanie M. Hoehl, James B. Macarthur, Peter A. Sims, Hongshen Ma, and Alexander H. Slocum. Robust and Economical Multi-sample, Multi-wavelength UV/vis Absorption and Fluorescence Detector for Biological and Chemical Contamination. AIP Advances 2, no. 3 (2012): 032110. https://orcid.org/0000-0002-5048-4109 en_US http://dx.doi.org/10.1063/1.4738962 AIP Advances Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use. application/pdf American Institute of Physics (AIP) Other University Web Domain |
| spellingShingle | Lu, Peter J. Macarthur, James B. Sims, Peter A. Ma, Hongshen Slocum, Alexander H. Hoehl, Melanie Margarete Robust and economical multi-sample, multi-wavelength UV/vis absorption and fluorescence detector for biological and chemical contamination |
| title | Robust and economical multi-sample, multi-wavelength UV/vis absorption and fluorescence detector for biological and chemical contamination |
| title_full | Robust and economical multi-sample, multi-wavelength UV/vis absorption and fluorescence detector for biological and chemical contamination |
| title_fullStr | Robust and economical multi-sample, multi-wavelength UV/vis absorption and fluorescence detector for biological and chemical contamination |
| title_full_unstemmed | Robust and economical multi-sample, multi-wavelength UV/vis absorption and fluorescence detector for biological and chemical contamination |
| title_short | Robust and economical multi-sample, multi-wavelength UV/vis absorption and fluorescence detector for biological and chemical contamination |
| title_sort | robust and economical multi sample multi wavelength uv vis absorption and fluorescence detector for biological and chemical contamination |
| url | http://hdl.handle.net/1721.1/79117 https://orcid.org/0000-0002-5048-4109 |
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