Simultaneous Reconstruction of Multiple Signaling Pathways via the Prize-Collecting Steiner Forest Problem

Signaling networks are essential for cells to control processes such as growth and response to stimuli. Although many “omic” data sources are available to probe signaling pathways, these data are typically sparse and noisy. Thus, it has been difficult to use these data to discover the cause of the d...

Full description

Bibliographic Details
Main Authors: Tuncbag, Nurcan, Braunstein, Alfredo, Pagnani, Andrea, Huang, Shao-Shan Carol, Chayes, Jennifer, Borgs, Christian, Zecchina, Riccardo, Fraenkel, Ernest
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:en_US
Published: Springer Science + Business Media B.V. 2013
Online Access:http://hdl.handle.net/1721.1/79429
https://orcid.org/0000-0001-9249-8181