Squishy Non-Spherical Hydrogel Microparticles
available in PMC 2011 July 15
| Main Authors: | , , |
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| Other Authors: | |
| Format: | Article |
| Language: | en_US |
| Published: |
John Wiley & Sons, Inc.
2013
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| Online Access: | http://hdl.handle.net/1721.1/79795 |
| _version_ | 1811087117140361216 |
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| author | Haghgooie, Ramin Toner, Mehmet Doyle, Patrick S. |
| author2 | Massachusetts Institute of Technology. Department of Chemical Engineering |
| author_facet | Massachusetts Institute of Technology. Department of Chemical Engineering Haghgooie, Ramin Toner, Mehmet Doyle, Patrick S. |
| author_sort | Haghgooie, Ramin |
| collection | MIT |
| description | available in PMC 2011 July 15 |
| first_indexed | 2024-09-23T13:40:23Z |
| format | Article |
| id | mit-1721.1/79795 |
| institution | Massachusetts Institute of Technology |
| language | en_US |
| last_indexed | 2024-09-23T13:40:23Z |
| publishDate | 2013 |
| publisher | John Wiley & Sons, Inc. |
| record_format | dspace |
| spelling | mit-1721.1/797952022-10-01T16:23:26Z Squishy Non-Spherical Hydrogel Microparticles Haghgooie, Ramin Toner, Mehmet Doyle, Patrick S. Massachusetts Institute of Technology. Department of Chemical Engineering Doyle, Patrick S. available in PMC 2011 July 15 Recent advances in the synthesis of polymeric colloids have opened the doors to new advanced materials. There is strong interest in using these new techniques to produce particles that mimic and/or interact with biological systems. An important characteristic of biological systems that has not yet been exploited in synthetic polymeric colloids is their wide range of deformability. A canonical example of this is the human red blood cell (RBC) which exhibits extreme reversible deformability under flow. Here we report the synthesis of soft polymeric colloids with sizes and shapes that mimic those of the RBC. Additionally, we demonstrate that the mechanical flexibility of the colloids can be reproducibly varied over a large range resulting in RBC-like deformability under physiological flow conditions. These materials have the potential to impact the interaction between biological and synthetic systems. Massachusetts Institute of Technology (MIT-MGH Fellowship in Translational Research) Massachusetts General Hospital (MIT-MGH Fellowship in Translational Research) National Institute of Biomedical Imaging and Bioengineering (U.S.) (BioMEMS Resource Center, P41 EB002503) John Simon Guggenheim Memorial Foundation Institut Curie (Rothschild-Yvette-Mayent-Institute Curie Fellowship) 2013-08-05T20:55:24Z 2013-08-05T20:55:24Z 2009-09 2009-07 Article http://purl.org/eprint/type/JournalArticle 10221336 15213927 http://hdl.handle.net/1721.1/79795 Haghgooie, Ramin, Mehmet Toner, and Patrick S. Doyle. Squishy Non-Spherical Hydrogel Microparticles. Macromolecular Rapid Communications (September 17, 2009): pp.128-134. en_US http://dx.doi.org/10.1002/marc.200900302 Macromolecular Rapid Communications Creative Commons Attribution-Noncommercial-Share Alike 3.0 http://creativecommons.org/licenses/by-nc-sa/3.0/ application/pdf John Wiley & Sons, Inc. PMC |
| spellingShingle | Haghgooie, Ramin Toner, Mehmet Doyle, Patrick S. Squishy Non-Spherical Hydrogel Microparticles |
| title | Squishy Non-Spherical Hydrogel Microparticles |
| title_full | Squishy Non-Spherical Hydrogel Microparticles |
| title_fullStr | Squishy Non-Spherical Hydrogel Microparticles |
| title_full_unstemmed | Squishy Non-Spherical Hydrogel Microparticles |
| title_short | Squishy Non-Spherical Hydrogel Microparticles |
| title_sort | squishy non spherical hydrogel microparticles |
| url | http://hdl.handle.net/1721.1/79795 |
| work_keys_str_mv | AT haghgooieramin squishynonsphericalhydrogelmicroparticles AT tonermehmet squishynonsphericalhydrogelmicroparticles AT doylepatricks squishynonsphericalhydrogelmicroparticles |