Rapid, modular and reliable construction of complex mammalian gene circuits

We developed a framework for quick and reliable construction of complex gene circuits for genetically engineering mammalian cells. Our hierarchical framework is based on a novel nucleotide addressing system for defining the position of each part in an overall circuit. With this framework, we demonst...

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Bibliographic Details
Main Authors: Guye, Patrick, Li, Yinqing, Wroblewska, Liliana, Duportet, Xavier, Weiss, Ron
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:en_US
Published: Oxford University Press 2013
Online Access:http://hdl.handle.net/1721.1/80718
https://orcid.org/0000-0003-0396-2443