Modeling the Insulin-Like Growth Factor System in Articular Cartilage

IGF signaling is involved in cell proliferation, differentiation and apoptosis in a wide range of tissues, both normal and diseased, and so IGF-IR has been the focus of intense interest as a promising drug target. In this computational study on cartilage, we focus on two questions: (i) what are the...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Zhang, Lihai, Smith, David W., Gardiner, Bruce S., Grodzinsky, Alan J.
Άλλοι συγγραφείς: Massachusetts Institute of Technology. Center for Biomedical Engineering
Μορφή: Άρθρο
Γλώσσα:en_US
Έκδοση: Public Library of Science 2013
Διαθέσιμο Online:http://hdl.handle.net/1721.1/80730
https://orcid.org/0000-0002-4942-3456