Modeling the Insulin-Like Growth Factor System in Articular Cartilage
IGF signaling is involved in cell proliferation, differentiation and apoptosis in a wide range of tissues, both normal and diseased, and so IGF-IR has been the focus of intense interest as a promising drug target. In this computational study on cartilage, we focus on two questions: (i) what are the...
Main Authors: | Zhang, Lihai, Smith, David W., Gardiner, Bruce S., Grodzinsky, Alan J. |
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Other Authors: | Massachusetts Institute of Technology. Center for Biomedical Engineering |
Format: | Article |
Language: | en_US |
Published: |
Public Library of Science
2013
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Online Access: | http://hdl.handle.net/1721.1/80730 https://orcid.org/0000-0002-4942-3456 |
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